Evidence map›Paper›PMID 34938382›Full record

ArticleOxidative medicine and cellular longevity2021

Selenium and Taurine Combination Is Better Than Alone in Protecting Lipopolysaccharide-Induced Mammary Inflammatory Lesions via Activating PI3K/Akt/mTOR Signaling Pathway by Scavenging Intracellular ROS.

Dandan Liu, Jiashan Lin, Wenmiao He, Kehe Huang

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  4. Review
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  12. Exosomes in Mastitis-Research Status, Opportunities, and Challenges.Animals : an open access journal from MDPI · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dandan LiuCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095 Jiangsu Province, China.ORCID https://orcid.org/0000-0002-0668-1631
Jiashan LinCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095 Jiangsu Province, China.ORCID https://orcid.org/0000-0001-9133-4791
Wenmiao HeCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095 Jiangsu Province, China.ORCID https://orcid.org/0000-0003-2347-1289
Kehe HuangCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095 Jiangsu Province, China.ORCID https://orcid.org/0000-0003-4132-3052
Nanjing Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mastitis is mainly induced by gram-negative bacterial infections, causing devastating economic losses to the global cattle industry. Both selenium (Se) and taurine (Tau) exhibit multiple biological effects, including reducing inflammation. However, no studies have reported the protective effect of the combined use of Se and Tau against mastitis, and the underlying mechanisms remain unclear. In this study, lipopolysaccharide (LPS), the vital virulence factor of gram-negative bacteria, was used to construct the

Indexed as

AnimalsAnti-Inflammatory AgentsCattleDrug Therapy, CombinationFemaleFree Radical ScavengersGene Expression RegulationInflammationLipopolysaccharidesMammary Glands, AnimalMastitisMiceMice, Inbred ICRPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReactive Oxygen SpeciesAnti-Inflammatory AgentsFree Radical ScavengersLipopolysaccharidesPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReactive Oxygen SpeciesSeleniumTaurineTOR Serine-Threonine Kinases

Identifiers

PMID34938382
PMCPMC8687852
OpenAlexW4200296194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.