Evidence map›Paper›PMID 34938354›Full record

Trial reportComputational and mathematical methods in medicine2021

Analysis of the Mechanism and Safety of Bisphosphonates in Patients with Lung Cancer and Bone Metastases.

Gao Zhang, Hu Gong, Hanqiao Xu

RetractedOpen access · hybridAbstract readRandomized Controlled TrialRetracted Publication
In one paragraph

Trial report in Computational and mathematical methods in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Gao ZhangDepartment of Oncology, General Hospital of Central Theater Command of Chinese People's Liberation Army, Hubei Wuhan 430070, China.
Hu GongDepartment of Orthopedics, Wuhan Sixth Hospital, Affiliated Hospital of Jianghan University, Hubei Wuhan 430015, China.
Hanqiao XuDepartment of Thoracic Surgery, Wuhan Sixth Hospital, Affiliated Hospital of Jianghan University, Hubei Wuhan 430015, China.ORCID https://orcid.org/0000-0001-5419-6174
Wuhan Sixth Hospital · CNChinese People's Liberation Army · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the mechanism and safety of bisphosphonates in patients with lung cancer and bone metastases.

methodA total of 104 patients with lung cancer and bone metastases in our hospital were selected and randomly divided into two groups: control group (

resultThe quality of life in both groups was significantly increased (

conclusionBisphosphonates have good effect on patients with lung cancer and bone metastases, which can improve anxiety and depression, reduce pain score, improve serum calcium level and immune function, and reduce inflammatory response. Therefore, bisphosphonate drug therapy is worth widely used.

Indexed as

AdultAgedAntineoplastic Combined Chemotherapy ProtocolsBone Density Conservation AgentsBone NeoplasmsCisplatinComputational BiologyDeoxycytidineDiphosphonatesFemaleGemcitabineHumansLung NeoplasmsMaleMiddle AgedQuality of LifeBone Density Conservation AgentsCisplatinDeoxycytidineDiphosphonatesGemcitabineZoledronic Acid

Identifiers

PMID34938354
PMCPMC8687786
OpenAlexW4200624695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.