Evidence map›Paper›PMID 34938157›Full record

ArticleFrontiers in neuroscience2021

Carbon Black Nanoparticles Selectively Alter Follicle-Stimulating Hormone Expression

Charlotte Avet, Emmanuel N Paul, Ghislaine Garrel, Valérie Grange-Messent, David L'Hôte, Chantal Denoyelle, Raphaël Corre, Jean-Marie Dupret, Sophie Lanone, Jorge Boczkowski and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Charlotte AvetUniversité de Paris, BFA, UMR 8251, CNRS, ERL U1133, Inserm, Paris, France.
Emmanuel N PaulInserm U955, IMRB, U 955, Faculté de Médecine, équipe 04, Université Paris Est (UPEC), Créteil, France.
Ghislaine GarrelUniversité de Paris, BFA, UMR 8251, CNRS, ERL U1133, Inserm, Paris, France.
Valérie Grange-MessentSorbonne Université, CNRS, Inserm, Neuroscience Paris Seine - Institut de Biologie Paris Seine, Paris, France.
David L'HôteUniversité de Paris, BFA, UMR 8251, CNRS, ERL U1133, Inserm, Paris, France.
Chantal DenoyelleUniversité de Paris, BFA, UMR 8251, CNRS, ERL U1133, Inserm, Paris, France.
Raphaël CorreUniversité de Paris, BFA, UMR 8251, CNRS, ERL U1133, Inserm, Paris, France.
Jean-Marie DupretUniversité de Paris, BFA, UMR 8251, CNRS, Paris, France.
Sophie LanoneInserm U955, IMRB, U 955, Faculté de Médecine, équipe 04, Université Paris Est (UPEC), Créteil, France.
Jorge BoczkowskiInserm U955, IMRB, U 955, Faculté de Médecine, équipe 04, Université Paris Est (UPEC), Créteil, France.
Violaine SimonUniversité de Paris, BFA, UMR 8251, CNRS, ERL U1133, Inserm, Paris, France.
Joëlle Cohen-TannoudjiUniversité de Paris, BFA, UMR 8251, CNRS, ERL U1133, Inserm, Paris, France.
Centre National de la Recherche Scientifique · FRInserm · FRUniversité Paris-Seine · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxic effects of nanoparticles on female reproductive health have been documented but the underlying mechanisms still need to be clarified. Here, we investigated the effect of carbon black nanoparticles (CB NPs) on the pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are key regulators of gonadal gametogenesis and steroidogenesis. To that purpose, we subjected adult female mice to a weekly non-surgical intratracheal administration of CB NPs at an occupationally relevant dose over 4 weeks. We also analyzed the effects of CB NPs

Indexed as

cAMP/PKA pathwaycarbon black nanoparticlesendocrine disruptionGnRHgonadotropinpituitary

Identifiers

PMID34938157
PMCPMC8685435
OpenAlexW4200023764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.