Evidence map›Paper›PMID 34938125›Full record

ArticleHIV/AIDS (Auckland, N.Z.)2021

Intestinal Parasitosis and its Association with CD4+ T Cell Count and Viral Load among People Living with HIV in Parasite Endemic Settings of Northwest Ethiopia.

Eseye Dereb, Markos Negash, Takele Teklu, Debasu Damtie, Aberham Abere, Firehiwot Kebede, Yalemwork Ewnetu, Eyuel Kasa

Open access · goldAbstract read
In one paragraph

Article in HIV/AIDS (Auckland, N.Z.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Eseye DerebUniversity of Gondar Comprehensive Specialized Hospital, Gondar, Ethiopia.
Markos NegashDepartment of Immunology and Molecular Biology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.ORCID 0000-0003-3685-2830
Takele TekluDepartment of Immunology and Molecular Biology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.ORCID 0000-0002-5306-6658
Debasu DamtieDepartment of Immunology and Molecular Biology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.ORCID 0000-0001-8517-7136
Aberham AbereDepartment of Medical Parasitology, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Firehiwot KebedeUniversity of Gondar Comprehensive Specialized Hospital, Gondar, Ethiopia.
Yalemwork EwnetuUniversity of Gondar Comprehensive Specialized Hospital, Gondar, Ethiopia.
Eyuel KasaUniversity of Gondar Comprehensive Specialized Hospital, Gondar, Ethiopia.
University of Gondar · ETWolaita Sodo University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study intestinal parasitosis and its association with viral load and CD4+ T cell count in HIV-infected individuals at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.

methodsA cross-sectional study was conducted from March to June 2019. Three hundred and sixteen study participants were selected using systematic random sampling technique. Sociodemographic and clinical data were collected using structured questionnaire. Stool samples were collected and examined using direct saline, formol ether concentration technique and modified acid fast staining. CD4+ T cell counts and viral load were determined by fluorescence-activated cell sorting (BD FACS) and COBAS Ampliprep/COBAS TaqMan HI2CAP assay, respectively. Data were entered into Epi Data 3.1 and transferred to SPSS version 20 software for analysis. Bivariable and multivariable analyses were performed using a binary logistic regression model. P values of less than 0.05 were considered statistically significant.

resultsThe overall prevalence of intestinal parasitosis was 24.7% (78/316). The most commonly detected parasite was

conclusionIn this study, prevalence of intestinal parasitic infections was high and was associated with low CD4+ T cell count and high viral load. Therefore, screening of HIV patients, especially those with low CD4+ T-cell count and high viral load, particularly for opportunistic intestinal parasitic infections would be of utmost importance in the efforts to prevent and control opportunistic infections in HIV patients.

Indexed as

CD4+HIVintestinal parasitosisNorthwest Ethiopiaviral load

Identifiers

PMID34938125
PMCPMC8685387
OpenAlexW4200247389

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.