ArticleThe Saudi dental journal2021
Effect of topical fluoride application and diode laser-irradiation on white spot lesions of human enamel.
Article in The Saudi dental journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Cariogenic Enamel Demineralization Prevention, Detection, and Management: A Literature Review.European journal of dentistry · 2026Article
- Investigating the effect of casein phosphopeptide-amorphous calcium phosphate, fluoride varnish, and diode laser on enamel microhardness.Dental research journal · 2026Article
- Laser-assisted Icon and clinpro for restoring white spot lesions: an in vitro comparative study.Odontology · 2025Article
- Assessment of Change in Enamel Color and Surface Hardness Following the Use of ICON Resin Infiltration and Remineralizing Agent: An In Vitro Study.Materials (Basel, Switzerland) · 2024Article
- Effect of Biomin F toothpaste and Diode laser on remineralization of white spot lesions (in vitro study).BMC oral health · 2024Article
- Effect of Diode Laser and Fluoride Varnish on Microhardness of enamel: An In Vitro Study.Journal of lasers in medical sciences · 2024Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aims to evaluate the effectiveness of topical fluoride application and diode laser-irradiation on the hardness of demineralized enamel and to evaluate the esthetic improvement of the white spot lesions (WSLs) using a visual analog scale (VAS). MATERIALS AND
methodsArtificial WSLs (3x3 mm) were created on the enamel surface of 45 human third molars. The teeth were randomly assigned into three groups (n = 15): group A, fluoride only; group B, combined therapy of fluoride and diode laser; and group C, control. Vicker's hardness number (VHN) was measured at baseline, after demineralization and after treatment. To evaluate the esthetic improvement after treatment, 14 raters evaluated each group's photographs using a 100-millimeter VAS. A one-way ANOVA or Brown-Forsythe and Games-Howell post hoc procedure were performed for statistical analysis. The level of significance was set at α = 0.05 for all tests.
resultsGroup A mean VHN was significantly higher than groups B and C, and group B was significantly higher than group C (P < 0.05). However, the mean VAS rating for the combined therapy group (B) was significantly higher than that for groups A and C (P < 0.05).
conclusionCombination therapy significantly improved the esthetic appearance of WSLs compared to the fluoride only group. However, there was less enamel hardness versus treatment with fluoride only.
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Registered trials
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