Evidence map›Paper›PMID 34937524›Full record

ArticlePathogens and global health2022

Enhancing efficacy of existing antibacterials against selected multiple drug resistant bacteria using cinnamic acid-coated magnetic iron oxide and mesoporous silica nanoparticles.

Noor Akbar, Muhammad Kawish, Tooba Jabri, Naveed Ahmed Khan, Muhammad Raza Shah, Ruqaiyyah Siddiqui

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens and global health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Antibacterial effects of quercetagetin are significantly enhanced upon conjugation with chitosan engineered copper oxide nanoparticles.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  2. Article
  3. Article
  4. Advances in Nanostructures for Antimicrobial Therapy.Materials (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Noor AkbarCollege of Arts and Sciences, American University of Sharjah, University City, Sharjah, UAE.
Muhammad KawishInternational Centre for Chemical and Biological Sciences, H.e.j. Research Institute of Chemistry, University of Karachi, Karachi, Pakistan.
Tooba JabriInternational Centre for Chemical and Biological Sciences, H.e.j. Research Institute of Chemistry, University of Karachi, Karachi, Pakistan.
Naveed Ahmed KhanDepartment of Clinical Sciences, College of Medicine, University of Sharjah, University City, Sharjah, UAE.ORCID 0000-0001-7667-8553
Muhammad Raza ShahInternational Centre for Chemical and Biological Sciences, H.e.j. Research Institute of Chemistry, University of Karachi, Karachi, Pakistan.
Ruqaiyyah SiddiquiCollege of Arts and Sciences, American University of Sharjah, University City, Sharjah, UAE.ORCID 0000-0001-9646-6208
University of Karachi · PKAmerican University of Sharjah · AEUniversity of Sharjah · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing new antibacterial drugs by using traditional ways is insufficient to meet existing challenges; hence, new strategies in the field of antibacterial discovery are necessary. An alternative strategy is to improve the efficacy of currently available antibiotics. Herein, the antibacterial efficacy of drugs (Cefixime, Sulfamethoxazole, and Moxifloxacin) and drug-loaded cinnamic acid-coated magnetic iron oxide and mesoporous silica nanoparticles (NPs) was elucidated versus Gram-negative bacteria (

Indexed as

Methicillin-Resistant Staphylococcus aureusNanoparticlesAnti-Bacterial AgentsCefiximeCinnamatesEscherichia coliFerric CompoundsHumansLactate DehydrogenasesMagnetic PhenomenaMethicillinMicrobial Sensitivity TestsMoxifloxacinProspective StudiesSilicon DioxideSulfamethoxazoleAnti-Bacterial AgentsCefiximeCinnamatescinnamic acidFerric Compoundsferric oxideLactate DehydrogenasesMethicillinMoxifloxacinSilicon DioxideSulfamethoxazoleAntibiotic resistancecytotoxicitydrug discoveryinfectious diseasesmagnetic nanoparticlesMBCmicmulti-drug resistancenanotechnology

Identifiers

PMID34937524
PMCPMC9518276
OpenAlexW4200573708

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.