Evidence map›Paper›PMID 34937192›Full record

ArticleMicrobiology spectrum2021

Cutibacterium acnes Induces the Expression of Immunosuppressive Genes in Macrophages and is Associated with an Increase of Regulatory T-Cells in Prostate Cancer.

Sabina Davidsson, Jessica Carlsson, Larry Greenberg, Jonny Wijkander, Bo Söderquist, Ann Erlandsson

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
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  10. Biology · 2025
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  13. 3-acetyl-11-keto-Materials today. Bio · 2025
    Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Prostate and urinary microbiomes in prostate cancer development: focus onFrontiers in cellular and infection microbiology · 2025
    Review
  19. Article
  20. Microbiota and urinary tumor immunity: Mechanisms, therapeutic implications, and future perspectives.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sabina DavidssonDepartment of Urology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.ORCID 0000-0002-2850-6009
Jessica CarlssonDepartment of Urology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Larry GreenbergDepartment of Environmental and Life Sciences/Biology, Faculty of Health, Science and Technology, Karlstad University, Karlstad, Sweden.
Jonny WijkanderDepartment of Health Sciences, Faculty of Health, Science and Technology, Karlstad University, Karlstad, Sweden.
Bo SöderquistSchool of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.ORCID 0000-0001-5939-2932
Ann ErlandssonDepartment of Urology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.ORCID 0000-0002-3813-9548
Örebro University · SEKarlstad University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumors and infectious agents both benefit from an immunosuppressive environment. Cutibacterium acnes (

Indexed as

B7-H1 AntigenChemokine CCL17Chemokines, CCEnzyme-Linked Immunospot AssayHumansImmune ToleranceMacrophagesMaleMicrobiotaPropionibacteriaceaeProstatic NeoplasmsT-Lymphocytes, RegulatoryTumor EscapeTumor MicroenvironmentB7-H1 AntigenCCL17 protein, humanCCL18 protein, humanCD274 protein, humanChemokine CCL17Chemokines, CCcancerCutibacterium acnesmacrophagesprostateprostate cancerregulatory T-cells

Identifiers

PMID34937192
PMCPMC8694172
OpenAlexW4200588289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.