Evidence map›Paper›PMID 34937179›Full record

ArticleMicrobiology spectrum2021

Phylogenetic Analysis with Prediction of Cofactor or Ligand Binding for Pseudomonas aeruginosa PAS and Cache Domains.

Andrew Hutchin, Charlotte Cordery, Martin A Walsh, Jeremy S Webb, Ivo Tews

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Andrew HutchinBiological Sciences, Institute for Life Sciences, University of Southamptongrid.5491.9, Southampton, United Kingdom.
Charlotte CorderyBiological Sciences, Institute for Life Sciences, University of Southamptongrid.5491.9, Southampton, United Kingdom.
Martin A WalshDiamond Light Source, Harwell Science and Innovation Campus, Didcot, United Kingdom.
Jeremy S WebbBiological Sciences, Institute for Life Sciences, University of Southamptongrid.5491.9, Southampton, United Kingdom.
Ivo TewsBiological Sciences, Institute for Life Sciences, University of Southamptongrid.5491.9, Southampton, United Kingdom.ORCID 0000-0002-4704-1139
Diamond Light Source · GBUniversity of Southampton · GBUniversité Libre de Bruxelles · BE

Funding

Biotechnology and Biological Sciences Research Council
6 · The paper itself

Abstract

PAS domains are omnipresent building blocks of multidomain proteins in all domains of life. Bacteria possess a variety of PAS domains in intracellular proteins and the related Cache domains in periplasmic or extracellular proteins. PAS and Cache domains are predominant in sensory systems, often carry cofactors or bind ligands, and serve as dimerization domains in protein association. To aid our understanding of the wide distribution of these domains, we analyzed the proteome of the opportunistic human pathogen Pseudomonas aeruginosa PAO1

Indexed as

Adaptation, PhysiologicalAmino Acid SequenceBacterial ProteinsGene Expression Regulation, BacterialHumansPhylogenyProtein BindingProtein ConformationProtein DomainsProteomeProteomicsPseudomonas aeruginosaBacterial ProteinsProteomeCache domaincofactorsPAS domainphylogenetic analysisphylogenyPseudomonassensory transduction processes

Identifiers

PMID34937179
PMCPMC8694187
OpenAlexW4200284487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.