Evidence map›Paper›PMID 34936541›Full record

ArticleAnnals of the American Thoracic Society2022

Secular and Regional Trends among Pulmonary Arterial Hypertension Clinical Trial Participants.

Jeff Min, Dina H Appleby, Robyn L McClelland, Jasleen Minhas, John H Holmes, Ryan J Urbanowicz, Steven C Pugliese, Jeremy A Mazurek, K Akaya Smith, Jason S Fritz and 4 more

Open access · greenAbstract read
In one paragraph

Article in Annals of the American Thoracic Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 6 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 6 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Medications for the treatment of pulmonary arterial hypertension: a systematic review and network meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022
    Pooled it
  6. Pooled it
  7. Article
  8. Article
  9. Pulmonary arterial hypertension in Latin America. The age and comorbidity paradox.International journal of cardiology. Congenital heart disease · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Jeff MinDepartment of Medicine and.ORCID 0000-0003-4633-6792
Dina H ApplebyDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; and.
Robyn L McClellandCollaborative Health Studies Coordinating Center, Department of Biostatistics, University of Washington, Seattle, Washington.
Jasleen MinhasDepartment of Medicine and.
John H HolmesDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; and.
Ryan J UrbanowiczDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; and.
Steven C PuglieseDepartment of Medicine and.
Jeremy A MazurekDepartment of Medicine and.
K Akaya SmithDepartment of Medicine and.
Jason S FritzDepartment of Medicine and.
Harold I PalevskyDepartment of Medicine and.
Jude Moutchia SuhDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; and.
Nadine Al-NaamaniDepartment of Medicine and.
Steven M KawutDepartment of Medicine and.
University of Pennsylvania · USUniversity of Washington · US

Funding

Cardiology & pulmonary research training grantT32HL007891 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Jason D Christie · 1998 to 2026
$12.0M
Mentored Patient-Oriented Research in Pulmonary Arterial HypertensionK24HL103844 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KAWUT, STEVEN M · 2011 to 2020
$1.6M
Obesity in Pulmonary Arterial HypertensionK23HL141584 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI AL-NAAMANI, NADINE · 2018 to 2022
$970k
NHLBI NIH HHS K23 HL141584NHLBI NIH HHS K24 HL103844NHLBI NIH HHS T32 HL007891
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Pulmonary Arterial HypertensionCohort StudiesEuropeFamilial Primary Pulmonary HypertensionFemaleHumansMaleObesityUnited Statesclinical trial participantspooled cohort analysispulmonary arterial hypertensionsecular trends

Identifiers

PMID34936541
PMCPMC9169130
OpenAlexW4200182720

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.