Evidence map›Paper›PMID 34936483›Full record

ArticleJournal of virology2022

Hypoxia and HIF-1 Trigger Marek's Disease Virus Reactivation in Lymphoma-Derived Latently Infected T Lymphocytes.

Corentin Mallet, Jade Cochard, Sébastien Leclercq, Laetitia Trapp-Fragnet, Philippe Chouteau, Caroline Denesvre

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Corentin MalletISP, INRAE, Université de Tours, Nouzilly, France.
Jade CochardINSERM U1259, Université de Tours and CHRU de Tours, Tours, France.
Sébastien LeclercqISP, INRAE, Université de Tours, Nouzilly, France.ORCID 0000-0002-3601-2316
Laetitia Trapp-FragnetISP, INRAE, Université de Tours, Nouzilly, France.
Philippe ChouteauINSERM U1259, Université de Tours and CHRU de Tours, Tours, France.
Caroline DenesvreISP, INRAE, Université de Tours, Nouzilly, France.ORCID 0000-0003-2241-8339
Université de Tours · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Latency is a hallmark of herpesviruses, allowing them to persist in their host without virion production. Acute exposure to hypoxia (below 3% O

Indexed as

Herpesvirus 2, GallidHypoxiaHypoxia-Inducible Factor 1Marek DiseaseT-LymphocytesVirus ActivationAnimalsCell Line, TumorChickensLymphomaHypoxia-Inducible Factor 1HIF-1hypoxialymphocytesMarek’s disease virusreactivation

Identifiers

PMID34936483
PMCPMC8906438
OpenAlexW4200299552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.