ArticleScience advances2021
At-home wireless monitoring of acute hemodynamic disturbances to detect sleep apnea and sleep stages via a soft sternal patch.
Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.
- Wearable Sensors and Artificial Intelligence for Sleep Apnea Detection: A Systematic Review.Journal of medical systems · 2025Pooled it
- Self-Powered All-in-One Wearable Bioelectronics Driven by Pneumatic Energy Buffering of Daily Footsteps.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Advances in Internal Organogenesis: Differentiation and Morphogenesis of Human Ventral Cavity Organs.Stem cell reviews and reports · 2026Review
- Conductive Hydrogel-Enabled Electrode for Scalp Electroencephalography Monitoring.Small methods · 2026Review
- Why sleep matters in chronic pain: evidence across the lifespan.EBioMedicine · 2026Review
- AI-enhanced flexible ECG patch for accurate heart disease diagnosis, optimal wear positioning, and interactive medical consultation.National science review · 2025Article
- A Novel Multi-Modal Flexible Headband System for Sleep Monitoring.Bioengineering (Basel, Switzerland) · 2025Article
- Hypnogram and Hypnodensity Analysis of REM Sleep Behaviour Disorder Using Both EEG and HRV-Based Sleep Staging Models.Journal of sleep research · 2025Article
- Elucidating the Reactivity of Reflectance-Based Core-Body Photoplethysmogram to Posture and Respiratory Changes.IEEE sensors journal · 2025Article
- Heart rate informed detection of cardiac events using the Kalman filter.Computers in biology and medicine · 2025Article
- Wireless Soft Athlete Bioelectronics for Monitoring Carbon Dioxide Ventilation and Physiological Performance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Applications of flexible materials in health management assisted by machine learning.RSC advances · 2025Review
- Emerging rapid detection methods for the monitoring of cardiovascular diseases: Current trends and future perspectives.Materials today. Bio · 2025Review
- Noninvasive Hemodynamic Assessment by a Sensor Patch: The PATCHWRK (PortAble TeCHnology for Wireless caRdiomyopathy tracKing) Study.JACC. Advances · 2025Article
- A crosslinked eutectogel for ultrasensitive pressure and temperature monitoring from nostril airflow.Nature communications · 2025Article
- Transforming Sleep Monitoring: Review of Wearable and Remote Devices Advancing Home Polysomnography and Their Role in Predicting Neurological Disorders.Biosensors · 2025Review
- Soft Nanomembrane Sensor-Enabled Wearable Multimodal Sensing and Feedback System for Upper-Limb Sensory Impairment Assistance.ACS nano · 2025Article
- What radio waves tell us about sleep!Sleep · 2025Article
- Printed Strain Sensors for Motion Recognition: A Review of Materials, Fabrication Methods, and Machine Learning Algorithms.IEEE open journal of engineering in medicine and biology · 2025Article
- Beyond Flexible: Unveiling the Next Era of Flexible Electronic Systems.Advanced materials (Deerfield Beach, Fla.) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
Obstructive sleep apnea (OSA) affects more than 900 million adults globally and can create serious health complications when untreated; however, 80% of cases remain undiagnosed. Critically, current diagnostic techniques are fundamentally limited by low throughputs and high failure rates. Here, we report a wireless, fully integrated, soft patch with skin-like mechanics optimized through analytical and computational studies to capture seismocardiograms, electrocardiograms, and photoplethysmograms from the sternum, allowing clinicians to investigate the cardiovascular response to OSA during home sleep tests. In preliminary trials with symptomatic and control subjects, the soft device demonstrated excellent ability to detect blood-oxygen saturation, respiratory effort, respiration rate, heart rate, cardiac pre-ejection period and ejection timing, aortic opening mechanics, heart rate variability, and sleep staging. Last, machine learning is used to autodetect apneas and hypopneas with 100% sensitivity and 95% precision in preliminary at-home trials with symptomatic patients, compared to data scored by professionally certified sleep clinicians.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.