ArticleThe Plant cell2022
Receptor-like cytoplasmic kinases PBL34/35/36 are required for CLE peptide-mediated signaling to maintain shoot apical meristem and root apical meristem homeostasis in Arabidopsis.
Article in The Plant cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Protein Phosphorylation: An Essential Role in Shoot Apical Meristem Homeostasis.Plants (Basel, Switzerland) · 2026Review
- Subtilase-mediated maturation of EPF1 and EPF2 is crucial for stomatal patterning.Nature plants · 2026Article
- The G protein-casein kinase 2 module acts as a pivot in plasma membrane-to-nucleus CLAVATA signaling to control shoot apical meristem size.Nature communications · 2026Article
- Motif-based substrate mapping of the receptor-like cytoplasmic kinase BIK1 reveals novel components and regulatory nodes of plant immunity.Nature plants · 2026Article
- Ubiquitination of BAM1 attenuates CLE peptide-mediated signaling in the root apical meristem.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Identification of Auxin-Associated Genes in Wheat Through Comparative Transcriptome Analysis and Validation of the Candidate Receptor-like Kinase GenePlants (Basel, Switzerland) · 2025Article
- Receptor kinase pathway signal tuning through a nontranscriptional incoherent feedforward loop.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Peptide hormones in plants.Molecular horticulture · 2025Review
- Heterotrimeric Gα-subunit regulates flower and fruit development in CLAVATA signaling pathway in cucumber.Horticulture research · 2024Article
- A novel toolbox to record CLE peptide signaling.Frontiers in plant science · 2024Article
- CLE peptide signaling in plant-microbe interactions.Frontiers in plant science · 2024Review
- Stem Cells: Engines of Plant Growth and Development.International journal of molecular sciences · 2023Review
- Genome-wide association analysis identifies natural allelic variants associated with panicle architecture variation in African rice, Oryza glaberrima Steud.G3 (Bethesda, Md.) · 2023Article
- A network of CLAVATA receptors buffers auxin-dependent meristem maintenance.Nature plants · 2023Article
- Modified Pseudo-Schiff Propidium Iodide for Staining the Shoot Apical Meristem inBio-protocol · 2023Article
- A phosphoinositide hub connects CLE peptide signaling and polar auxin efflux regulation.Nature communications · 2023Article
- Mutation ofFrontiers in plant science · 2023Article
- Few-Shot Learning Enables Population-Scale Analysis of Leaf Traits inPlant phenomics (Washington, D.C.) · 2023Article
- As above, so below: CLE peptide signaling in shoot and root apical meristems.The Plant cell · 2022Article
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12 authors.
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Abstract
Shoot apical meristem (SAM) and root apical meristem (RAM) homeostasis is tightly regulated by CLAVATA3 (CLV3)/EMBRYO SURROUNDING REGION-related (CLE) peptide signaling. However, the intracellular signaling components after CLV3 is perceived by the CLV1-CLV3-INSENSITIVE KINASE (CIK) receptor complex and CLE25/26/45 are sensed by the BARELY ANY MERISTEM (BAM)-CIK receptor complex are unknown. Here, we report that PBS1-LIKE34/35/36 (PBL34/35/36), a clade of receptor-like cytoplasmic kinases, are required for both CLV3-mediated signaling in the SAM and CLE25/26/45-mediated signaling in the RAM. Physiological assays showed that the SAM and RAM of pbl34 pbl35 pbl36 were resistant to CLV3 and CLE25/26/45 treatment, respectively. Genetic analyses indicated that pbl34 pbl35 pbl36 greatly enhanced the SAM defects of clv2 and rpk2 but not clv1, and did not show additive effects with bam3 and cik2 in the RAM. Further biochemical assays revealed that PBL34/35/36 interacted with CLV1, BAM1/3, and CIKs, and were phosphorylated by CLV1 and BAM1. All these results suggest that PBL34/35/36 act downstream of CLV1 and BAM1/3 to mediate the CLV3 and CLE25/26/45 signals in maintaining SAM and RAM homeostasis, respectively. Our findings shed light on how CLE signals are transmitted intracellularly after being perceived by cell surface receptor complexes.
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