Evidence map›Paper›PMID 34935567›Full record

ArticleClinical toxicology (Philadelphia, Pa.)2022

Impact of marijuana legalization on cannabis-related visits to the emergency department.

Nicole V Tolan, Tolumofe Terebo, Peter R Chai, Timothy B Erickson, Bryan D Hayes, Sacha N Uljon, Athena K Petrides, Christiana A Demetriou, Stacy E F Melanson

Open access · greenAbstract read
In one paragraph

Article in Clinical toxicology (Philadelphia, Pa.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  5. Trends in cannabis use in New Jersey: Effects of COVID-19 and cannabis legalization.Journal of the American College of Emergency Physicians open · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Nicole V TolanDepartment of Pathology, Brigham and Women's Hospital, Boston, MA, USA.ORCID 0000-0002-7239-1843
Tolumofe TereboDepartment of Pathology, Brigham and Women's Hospital, Boston, MA, USA.ORCID 0000-0002-6041-9458
Peter R ChaiHarvard Medical School, Boston, MA, USA.ORCID 0000-0003-0955-4117
Timothy B EricksonHarvard Medical School, Boston, MA, USA.ORCID 0000-0002-1809-4805
Bryan D HayesHarvard Medical School, Boston, MA, USA.ORCID 0000-0001-7349-6770
Sacha N UljonHarvard Medical School, Boston, MA, USA.ORCID 0000-0001-5190-6652
Athena K PetridesDepartment of Pathology, Brigham and Women's Hospital, Boston, MA, USA.
Christiana A DemetriouDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
Stacy E F MelansonDepartment of Pathology, Brigham and Women's Hospital, Boston, MA, USA.ORCID 0000-0002-4209-6085
Brigham and Women's Hospital · USHarvard University · USUniversity of Nicosia · CY

Funding

Smart Steps: A context-aware adherence intervention to improve PrEP adherence among men who have sex with men (MSM) with substance use disorderDP2DA056107 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAI, PETER R · 2022 to 2022
$2.7M
A novel robotic wastewater analysis system to quantify opioid exposure and treatment in residential communitiesR44DA051106 · NIDA · BIOBOT ANALYTICS, INC. · PI CHAI, PETER R, MATUS GARCIA, MARIANA G · 2020 to 2022
$1.5M
Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance UsersK23DA044874 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAI, PETER R · 2018 to 2022
$1.0M
NIDA NIH HHS DP2 DA056107NIDA NIH HHS K23 DA044874NIDA NIH HHS R44 DA051106
6 · The paper itself

Abstract

backgroundCannabis is widely used in the United States despite federal laws. In US states that have progressed toward legalization, there have been various reported impacts on cannabis-related emergency department (ED) visits. However, studies on the impact of legalization in Massachusetts (MA) EDs are lacking.

methodsCannabinoid immunoassay (THC IA) results and cannabis-related ICD-10 codes were obtained for consecutive patient ED visits at two academic medical centers in Boston, MA over the following legalization periods (January 2012-December 2019): decriminalized (DEC), before medical dispensaries (MED BD), medical dispensaries available (MED DISP), before recreational dispensaries (REC BD) and recreational dispensaries available (REC DISP). Trends and monthly positivity rates for THC IA and ICD-10 codes were determined for these legalization periods.

resultsThere was an increase in both THC IA (

conclusionsLegalization of marijuana in MA has led to an increase in cannabis use as indicated by both increasing rates of positive THC IA results, in older adults, as well as increasing cannabis-related ICD-10 codes. Data suggest a steady increase in THC use associated with legalization that was not associated with an increase in opiate, fentanyl, or cocaine use. We recommend using ED THC IA positivity, an objective laboratory measure, to monitor THC use and the impact of state-specific progression in cannabis legalization.

Indexed as

CannabisHallucinogensMedical MarijuanaAdultAgedAnalgesicsEmergency Service, HospitalFemaleHumansLegislation, DrugUnited StatesAnalgesicsHallucinogensMedical MarijuanacannabisICD-10legalizationMarijuanatetrahydrocannabinolurine drug screen

Identifiers

PMID34935567
PMCPMC8957546
OpenAlexW4200450943

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.