Evidence map›Paper›PMID 34935421›Full record

SynthesisMicrobiology spectrum2021

Expanding the Colorectal Cancer Biomarkers Based on the Human Gut Phageome.

Siyuan Shen, Dongxue Huo, Chenchen Ma, Shuaiming Jiang, Jiachao Zhang

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Siyuan ShenCollege of Food Science and Engineering, Hainan Universitygrid.428986.9, Haikou, China.
Dongxue HuoCollege of Food Science and Engineering, Hainan Universitygrid.428986.9, Haikou, China.
Chenchen MaCollege of Food Science and Engineering, Hainan Universitygrid.428986.9, Haikou, China.
Shuaiming JiangCollege of Food Science and Engineering, Hainan Universitygrid.428986.9, Haikou, China.
Jiachao ZhangCollege of Food Science and Engineering, Hainan Universitygrid.428986.9, Haikou, China.ORCID 0000-0001-8099-6749
Hainan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the increasing prevalence of colorectal cancer (CRC), extending the present biomarkers for the diagnosis of colorectal cancer is crucial. Previous studies have highlighted the importance of bacteriophages in gastrointestinal diseases, suggesting the potential value of gut phageome in early CRC diagnostic. Here, based on 317 metagenomic samples of three discovery cohorts collected from China (Hong Kong), Austria, and Japan, five intestinal bacteriophages, including Fusobacterium nucleatum,

Indexed as

ViromeAustriaBacteriophagesBiomarkers, TumorChinaCohort StudiesColitis, UlcerativeColorectal NeoplasmsCrohn DiseaseFecesGastrointestinal TractHumansJapanMetagenomeBiomarkers, Tumorbacteriophagebiomarkerscolorectal cancermetagenome

Identifiers

PMID34935421
PMCPMC8693921
OpenAlexW4200076330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.