Evidence map›Paper›PMID 34935415›Full record

ArticleMicrobiology spectrum2021

The

Martin Gélinas, Léa Museau, Arielle Milot, Pascale B Beauregard

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Synergistic inhibition ofFrontiers in microbiology · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Indolenine-substituted pyrazole derivative 4e inhibits planktonicAntimicrobial agents and chemotherapy · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Antibacterial and antibiofilm activities and mechanisms ofCurrent research in food science · 2025
    Article
  17. Machine learning and network analysis with focus on the biofilm inComputational and structural biotechnology journal · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Martin GélinasUniversité de Sherbrookegrid.86715.3d, Département de biologie, Faculté des sciences, Sherbrooke, Québec, Canada.
Léa MuseauUniversité de Sherbrookegrid.86715.3d, Département de biologie, Faculté des sciences, Sherbrooke, Québec, Canada.
Arielle MilotUniversité de Sherbrookegrid.86715.3d, Département de biologie, Faculté des sciences, Sherbrooke, Québec, Canada.
Pascale B BeauregardUniversité de Sherbrookegrid.86715.3d, Département de biologie, Faculté des sciences, Sherbrooke, Québec, Canada.ORCID 0000-0003-2947-0500
Université de Sherbrooke · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial biofilms are involved in chronic infections and confer 10 to 1,000 times more resistance to antibiotics compared with planktonic growth, leading to complications and treatment failure. When transitioning from a planktonic lifestyle to biofilms, some Gram-positive bacteria are likely to modulate several cellular pathways, including central carbon metabolism, biosynthesis pathways, and production of secondary metabolites. These metabolic adaptations might play a crucial role in biofilm formation by Gram-positive pathogens such as Staphylococcus aureus and Enterococcus faecalis. Here, we performed a transcriptomic approach to identify cellular pathways that might be similarly regulated during biofilm formation in these bacteria. Different strains and biofilm-inducing media were used to identify a set of regulated genes that are common and independent of the environment or accessory genomes analyzed. Our approach highlighted that the

Indexed as

BiofilmsBacterial ProteinsBiosynthetic PathwaysCulture MediaEnterococcus faecalisGram-Positive Bacterial InfectionsHumansPurinesStaphylococcal InfectionsStaphylococcus aureusBacterial ProteinsCulture MediapurinePurines29212biofilmEnterococcus faecalispurin biosynthesis pathwaySH1000Staphylococcus aureustranscriptomicUSA300V583

Identifiers

PMID34935415
PMCPMC8693917
OpenAlexW4200216254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.