Evidence map›Paper›PMID 34935258›Full record

ArticleHealth expectations : an international journal of public participation in health care and health policy2022

Swallowing the pill of adverse effects: A qualitative study of patients' and pharmacists' experiences and decision-making regarding the adverse effects of chronic pain medications.

Lise Dassieu, Emilie Paul-Savoie, Élise Develay, Ana Cecilia Villela Guilhon, Anaïs Lacasse, Line Guénette, Kadija Perreault, Hélène Beaudry, Laurent Dupuis, Quebec Consortium on Adverse Effects of Pain Medications

Open access · goldAbstract read
In one paragraph

Article in Health expectations : an international journal of public participation in health care and health policy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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  8. 'What price do you put on your health?': Medical cannabis, financial toxicity and patient perspectives on medication access in advanced cancer.Health expectations : an international journal of public participation in health care and health policy · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Lise DassieuResearch Center of the Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.ORCID 0000-0002-6311-3681
Emilie Paul-SavoieQuebec Pain Research Network, Sherbrooke, Quebec, Canada.
Élise DevelayResearch Center of the Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Ana Cecilia Villela GuilhonResearch Center of the Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Anaïs LacasseQuebec Pain Research Network, Sherbrooke, Quebec, Canada.
Line GuénetteQuebec Pain Research Network, Sherbrooke, Quebec, Canada.
Kadija PerreaultQuebec Pain Research Network, Sherbrooke, Quebec, Canada.
Hélène BeaudryQuebec Pain Research Network, Sherbrooke, Quebec, Canada.
Laurent DupuisQuebec Pain Research Network, Sherbrooke, Quebec, Canada.
Quebec Consortium on Adverse Effects of Pain Medications
Quebec Rehabilitation Research Network · CAUniversité de Sherbrooke · CACentre for Interdisciplinary Research in Rehabilitation · CACentre Hospitalier de l’Université de Montréal · CAUniversité du Québec en Abitibi-Témiscamingue · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPharmacological treatments of chronic pain can lead to numerous and sometimes serious adverse effects. Drawing on a social science approach to chronic illness, this study aimed to understand the experiences of people living with chronic pain and community pharmacists regarding the definition, prevention and management of analgesic adverse effects.

methodsThis qualitative study proceeded through 12 online focus groups (FGs) with people living with chronic pain (n = 26) and community pharmacists (n = 19), conducted between July 2020 and February 2021 in the province of Quebec, Canada. The semistructured discussion guides covered participants' definitions of adverse effects and decision-making regarding their prevention and management. Discussions were audio-recorded, transcribed verbatim and analysed using grounded theory.

resultsBoth people with chronic pain and pharmacists provided varying definitions of analgesic adverse effects depending on patients' social and clinical characteristics. Present quality of life and serious long-term risks related to treatment were described as key dimensions influencing adverse effect appraisal. Dilemmas and discrepancies occurred between patients and pharmacists when choosing to prioritize pain relief or adverse effect prevention. Some patients lacked information about their medications and wanted to be more involved in decisions, while many pharmacists were concerned by patients' self-management of adverse effects. Preventing opioid-related overdoses often led pharmacists to policing practices. Despite most pharmacists wishing they could have a key role in the management of pain and adverse effects face organizational and financial barriers.

conclusionDefining, preventing and managing adverse effects in the treatment of chronic pain requires a person-centred approach and shared decision-making. Clinical training improvements and healthcare organization changes are needed to support pharmacists in providing patients with community-based follow-up and reliable information about the adverse effects of chronic pain treatments. PATIENT OR PUBLIC CONTRIBUTION: A person with lived experience of chronic pain was involved as a coinvestigator in the study. He contributed to shaping the study design and objectives, including major methodological decisions such as the choice of pharmacists as the most appropriate professionals to investigate. In addition, 26 individuals with chronic pain shared their experiences extensively during the FGs.

Indexed as

Chronic PainCommunity Pharmacy ServicesDeglutitionHumansMalePharmacistsProfessional RoleQuality of Lifeadverse effectsanalgesicschronic paincommunity pharmacistsdecision-makingperson-centred carequalitative research

Identifiers

PMID34935258
PMCPMC8849270
OpenAlexW4200477775

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.