ArticleNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition2022
Monitor gastrointestinal tolerance in children who have switched to an "enteral formula with food-derived ingredients": A national, multicenter retrospective chart review (RICIMIX study).
Article in Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 29 citations in OpenAlex.
- Association between blenderized tube feeds and differential oropharynx, stomach, and stool microbiome signatures relative to conventional formula feeds in children fed via enteral tube: A cross-sectional study.JPEN. Journal of parenteral and enteral nutrition · 2026Article
- Food-based formula modulates gut microbial homeostasis and inflammatory responses following LPS challenge in mice.Frontiers in nutrition · 2026Article
- Nutrition Support Interventions for Children and Young People Treated for Osteosarcoma: A Scoping Review.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025Article
- Clinical and Gut Microbiome Characteristics of Medically Complex Patients Receiving Blenderized Tube Feeds vs. Standard Enteral Feeds.Nutrients · 2025Article
- Experiences and perceptions of multidisciplinary paediatric teams of blended tube feeding in children.Nutrition and health · 2025Observational
- The impact of an enteral formula with food-derived ingredients on dietetic practice at a specialist children's hospital in the UK: Retrospective study.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025Article
- Case Report: Food-based enteral formula in the nutritional management of children with hyperinsulinism: single center retrospective case series.Frontiers in endocrinology · 2025Article
- Gut dysmotility in children with neurological impairment: the nutritional management.Frontiers in neurology · 2023Review
- Enteral formula compared to Nissen-Fundoplication: Data from a retrospective analysis on tolerance, utility, applicability, and safeness in children with neurological diseases.Frontiers in nutrition · 2023Article
- Review
- Monitor gastrointestinal tolerance in children who have switched to an "enteral formula with food-derived ingredients": A national, multicenter retrospective chart review (RICIMIX study).Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2022Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundEnteral tube feeding intolerances, such as diarrhea, are commonly reported in children. In the pediatric population, interest is growing in the use of blended diets for the management of enteral feeding intolerances. Fiber within a blended diet stimulates the growth of beneficial gut bacteria, which in turn produce short-chain fatty acids, which are utilized as energy substrates for enterocytes. Enteral formula manufacturers have responded to this trend towards "real-food" blended diets and developed an enteral formula with food-derived ingredients. The aim of this study was to collect data relating to feed tolerance in children who had switched to an "enteral formula with food-derived ingredients."
methodsA national multicenter retrospective study.
resultsDietitians collected data from 43 medically unwell children between March 2021 and July 2021. Significant improvements were reported in children who had switched to an "enteral formula with food-derived ingredients" in retching 17 of 18 children (95%), flatulence 6 of 8 children (85%), loose stools 10 of 11 children (90%), and constipation 10 of 11 children (90%). These improvements in gastrointestinal symptoms were reflected in weight change during the one month period measurements were collected (baseline, 19.5 kg [SD, 9]; 1 month, 20.1 kg [SD, 9]; P = 0.002).
conclusionWe have observed beneficial outcomes in medically complex children who have switched to an "enteral formula with food-derived ingredients." Our data should motivate healthcare professionals to implement more research to better evaluate the clinical impact and mechanisms of action of blended diets and enteral formulas with food-derived ingredients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.