Evidence map›Paper›PMID 34935159›Full record

ArticleThe EMBO journal2022

Caldendrin and myosin V regulate synaptic spine apparatus localization via ER stabilization in dendritic spines.

Anja Konietzny, Jasper Grendel, Alan Kadek, Michael Bucher, Yuhao Han, Nathalie Hertrich, Dick H W Dekkers, Jeroen A A Demmers, Kay Grünewald, Charlotte Uetrecht and 1 more

Open access · hybridAbstract read
In one paragraph

Article in The EMBO journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Neuronal Golgi Network and Its Acolytes.Sub-cellular biochemistry · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. L-type CaProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Article
  11. Caldendrin Is a Repressor of PIEZO2 Channels and Touch Sensation in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  12. Review
  13. Molecular Mechanisms of AMPA Receptor Trafficking in the Nervous System.International journal of molecular sciences · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Anja KonietznyRG Optobiology, Institute of Biology, Humboldt Universität zu Berlin, Berlin, Germany.
Jasper GrendelRG Optobiology, Institute of Biology, Humboldt Universität zu Berlin, Berlin, Germany.
Alan KadekLeibniz Institute for Experimental Virology (HPI), Hamburg, Germany.ORCID 0000-0002-7953-5870
Michael BucherRG Optobiology, Institute of Biology, Humboldt Universität zu Berlin, Berlin, Germany.
Yuhao HanRG Optobiology, Institute of Biology, Humboldt Universität zu Berlin, Berlin, Germany.
Nathalie HertrichRG Optobiology, Institute of Biology, Humboldt Universität zu Berlin, Berlin, Germany.
Dick H W DekkersCenter for Proteomics, Erasmus MC, Rotterdam, The Netherlands.
Jeroen A A DemmersCenter for Proteomics, Erasmus MC, Rotterdam, The Netherlands.
Kay GrünewaldLeibniz Institute for Experimental Virology (HPI), Hamburg, Germany.
Charlotte UetrechtLeibniz Institute for Experimental Virology (HPI), Hamburg, Germany.
Marina MikhaylovaRG Optobiology, Institute of Biology, Humboldt Universität zu Berlin, Berlin, Germany.ORCID 0000-0001-7646-1346
Universität Hamburg · DELeibniz Institute of Virology (LIV) · DEErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excitatory synapses of principal hippocampal neurons are frequently located on dendritic spines. The dynamic strengthening or weakening of individual inputs results in structural and molecular diversity of dendritic spines. Active spines with large calcium ion (Ca

Indexed as

ActinsAnimalsCalcium-Binding ProteinsCalmodulinDendritic SpinesEndoplasmic ReticulumEndoplasmic Reticulum, SmoothHEK293 CellsHippocampusHumansMass SpectrometryMiceMice, KnockoutMyosin Type VProtein Interaction Domains and MotifsRatsActinsCa2+-binding protein-1Calcium-Binding ProteinsCalmodulinMyosin Type Vcaldendrinendoplasmic reticulummyosinspine apparatussynapse

Identifiers

PMID34935159
PMCPMC8844991
OpenAlexW4200132225

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.