ArticleBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine2022
Cytotoxic cobalt (III) Schiff base complexes: in vitro anti-proliferative, oxidative stress and gene expression studies in human breast and lung cancer cells.
Article in Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 36 citations in OpenAlex.
- Review
- Hybrid Ammonium-M(II) Hydrogenophosphite Hydrates as Bioactive Metal Complexes: Synthesis, DFT and Hirshfeld Surface Analysis, and Anticancer and Anti-Inflammatory Activities.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Mechanistic Exploration of the anticancer activity of Justicia adhatoda Plant Leaf Ethanolic Extract against Colon Cancer Cells: An in silico and in vitro Approach.Asian Pacific journal of cancer prevention : APJCP · 2026Article
- Article
- Enhancing the Cytotoxicity and Apoptotic Efficacy of Parasporin-2-Derived Variants (Mpp46Aa1) on Cancer Cell Lines.Toxins · 2024Article
- Exploiting Co(III)-Cyclopentadienyl Complexes To Develop Anticancer Agents.Inorganic chemistry · 2024Article
- A Comparison ofInorganica chimica acta · 2024Article
- In vitro bio-characterization of solid lipid nanoparticles of favipiravir in A549 human lung epithelial cancer cells.Journal of Taibah University Medical Sciences · 2023Article
- Equilibria of complexes in the aqueous cobalt(II)-Computational and structural biotechnology journal · 2023Article
- Promising Schiff bases in antiviral drug design and discovery.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2023Review
- Metal Complexes with Schiff Bases: Data Collection and Recent Studies on Biological Activities.International journal of molecular sciences · 2022Review
- Cobalt (III) complex exerts anti-cancer effects on T cell lymphoma through induction of cell cycle arrest and promotion of apoptosis.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2022Article
- Dual Roles of Coconut Oil and Its Major Component Lauric Acid on Redox Nexus: Focus on Cytoprotection and Cancer Cell Death.Frontiers in neuroscience · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing cancer drug chemo-resistance, especially in the treatment of breast and lung cancers, alarms the immediate need of newer and effective anticancer drugs. Until now, chemotherapeutics based on metal complexes are considered the most effective treatment modality. In the present study, we have evaluated the cytotoxic effect of two cobalt (III) Schiff base complexes based on the leads from complex combinatorial chemistry. Cobalt (III) Schiff base complexes (Complex 3 = Co(Ph-acacen)(HA)
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Registered trials
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