Evidence map›Paper›PMID 34934980›Full record

ArticleF&S reports2021

Birthweight associations with parental obesity: retrospective analysis of 1,778 singleton term births following assisted reproductive treatment.

Nicole O McPherson, Andrew D Vincent, Deirdre Zander-Fox, Jessica A Grieger

Abstract read
In one paragraph

Article in F&S reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicole O McPhersonFreemasons Center for Male Health and Wellbeing, University of Adelaide, South Australia, Australia.
Andrew D VincentFreemasons Center for Male Health and Wellbeing, University of Adelaide, South Australia, Australia.
Deirdre Zander-FoxRobinson Research Institute, University of Adelaide, South Australia, Australia.
Jessica A GriegerRobinson Research Institute, University of Adelaide, South Australia, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the association of combined parental preconception overweight and obesity on infant birthweight.

designRetrospective study of fresh in vitro fertilization or intracytoplasmic sperm injection cycles (2009-2017).

settingRepromed, South Australia, assisted reproductive technology clinic. PATIENTS: Couples undergoing in vitro fertilization/intracytoplasmic sperm injection insemination with their own gametes and transfer of a fresh single blastocyst (N = 1,778).

interventionsNone.

main outcome measuresParental body mass index (BMI) was recorded prior to cycle initiation. Infant birthweight was recorded at delivery. The impact of parental obesity and their interaction on first singleton term (≥37 weeks' gestation) birthweight was assessed using linear regressions assessing nonlinearity and a pairwise linear interactions.

resultsIn the base model where parental BMI is assumed linear, there was strong evidence for higher birthweight with increasing maternal BMI (11.2 g per maternal kg/m

conclusionsIncreases in the mean infant birthweight associated with maternal obesity are attenuated when the father is obese. While maternal BMI contributed more to the mean infant birthweight than paternal BMI, a couple-centered approach to preconception health advice is recommended, given the documented relationships between parental obesity and childhood weight beyond infancy. Further studies in both assisted reproductive technology and general population cohorts assessing the parental BMI interaction on infant birthweight are warranted.

Indexed as

body mass indexMaternal obesityoffspring birthweightpaternal obesitypreconception

Identifiers

PMID34934980
PMCPMC8655430

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.