ArticleF&S reports2021
Impact of an online multicomponent very-low-carbohydrate program in women with polycystic ovary syndrome: a pilot study.
Article in F&S reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03987854 (The University of Michigan PCOS Intervention Using Nutritional Ketosis), which is not on this map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The University of Michigan PCOS Intervention Using Nutritional Ketosis
Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Review
- Article
- Mental Health Across the Menstrual Cycle in Polycystic Ovary Syndrome: Insights and Implications.Current psychiatry reports · 2024Review
- The impact of ketogenic diet on some metabolic and non-metabolic diseases: Evidence from human and animal model experiments.Food science & nutrition · 2024Review
- The role of meditation and mindfulness in the management of polycystic ovary syndrome: a scoping review.Frontiers in endocrinology · 2024Article
- Diet and fertility: take it with a grain of salt?F&S reports · 2021Article
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveTo study the impact of a very-low-carbohydrate (VLC) diet for 16 weeks in overweight or obese women with polycystic ovary syndrome (PCOS).
designSingle-arm prospective pilot study.
settingWe recruited participants using medical records from an academic medical center. PATIENTS: Twenty-nine overweight or obese women (body mass index, 25-50 kg/m
interventionsWe taught participants to follow a VLC diet and provided information about a variety of behavioral skills including mindfulness and positive affect using an online 16-week intervention.
main outcome measuresChanges in body weight, glycated hemoglobin, and PCOS-related quality of life.
resultsThe intervention led to positive health outcomes including decreases in percent weight (mean difference = -7.67, SD = 6.10) and glycated hemoglobin level (mean difference = -0.21%, SD = 0.27), an increase in sex hormone binding globulin level (mean difference = 9.24 nmol/L, SD = 16.34), and increases in PCOS-related quality of life measures, including menstrual predictability (mean difference = 2.10, SD = 2.76) and body hair (mean difference = 1.14, SD = 1.04). The low-density lipoprotein cholesterol level increased (mean difference = 0.23 mmol/L, SD = 0.49).
conclusionsThe results suggest that a VLC dietary intervention has potential to promote both weight loss and glycemic control in overweight and obese adults with PCOS, two key components in the prevention of type 2 diabetes. TRIAL REGISTRATION NUMBER: NCT03987854.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.