Evidence map›Paper›PMID 34934890›Full record

ArticleEnvironmental epidemiology (Philadelphia, Pa.)2021

Geographical Variations of the Minimum Mortality Temperature at a Global Scale: A Multicountry Study.

Aurelio Tobías, Masahiro Hashizume, Yasushi Honda, Francesco Sera, Chris Fook Sheng Ng, Yoonhee Kim, Dominic Roye, Yeonseung Chung, Tran Ngoc Dang, Ho Kim and 57 more

Abstract read
In one paragraph

Article in Environmental epidemiology (Philadelphia, Pa.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Building the model: a review of input structures in extreme temperature-health.Environmental health : a global access science source · 2026
    Pooled it
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  18. Ten new insights in climate science 2024.One earth (Cambridge, Mass.) · 2025
    Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

67 authors.

Aurelio TobíasInstitute of Environmental Assessment and Water Research (IDAEA), Spanish Council for Scientific Research (CSIC), Barcelona, Spain.
Masahiro HashizumeDepartment of Global Health Policy, Graduate School of Medicine, The University of Tokyo, Tokyo.
Yasushi HondaCenter for Climate Change Adaptation, National Institute for Environmental Studies, Tsukuba, Japan.
Francesco SeraDepartment of Statistics, Computer Science and Applications "G. Parenti," University of Florence, Florence, Italy.
Chris Fook Sheng NgSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki.
Yoonhee KimDepartment of Global Environmental Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Dominic RoyeDepartment of Geography, University of Santiago de Compostela, Santiago de Compostela, Spain.
Yeonseung ChungDepartment of Mathematical Sciences, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.
Tran Ngoc DangDepartment of Environmental Health, Faculty of Public Health, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Ho KimGraduate School of Public Health, Seoul National University, Seoul, Republic of Korea.
Whanhee LeeSchool of the Environment, Yale University, New Haven, Connecticut.
Carmen ÍñiguezDepartment of Statistics and Computational Research. Universitat de València, València, Spain.
Ana Vicedo-CabreraInstitute of Social and Preventive Medicine.
Rosana AbrutzkyUniversidad de Buenos Aires, Facultad de Ciencias Sociales, Instituto de Investigaciones Gino Germani, Buenos Aires.
Yuming GuoDepartment of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne.
Shilu TongSchool of Public Health and Social Work, Queensland University of Technology, Brisbane, Australia.
Micheline de Sousa Zanotti Stagliorio CoelhoDepartment of Pathology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
Paulo Hilario Nascimento SaldivaDepartment of Pathology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
Eric LavigneSchool of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
Patricia Matus CorreaDepartment of Public Health, Universidad de los Andes, Santiago, Chile.
Nicolás Valdés OrtegaDepartment of Public Health, Universidad de los Andes, Santiago, Chile.
Haidong KanDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai, China.
Samuel OsorioDepartment of Environmental Health, University of São Paulo, São Paulo, Brazil.
Jan KyselýInstitute of Atmospheric Physics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Aleš UrbanInstitute of Atmospheric Physics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Hans OrruDepartment of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Ene IndermitteDepartment of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Jouni J K JaakkolaCenter for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland.
Niilo R I RytiCenter for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland.
Mathilde PascalSanté Publique France, Department of Environmental Health, French National Public Health Agency, Saint Maurice, France.
Veronika HuberDepartment of Physical, Chemical and Natural Systems, Universidad Pablo de Olavide, Sevilla, Spain.
Alexandra SchneiderInstitute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
Klea KatsouyanniDepartment of Hygiene, Epidemiology and Medical Statistics, National and Kapodistrian University of Athens, Greece.
Antonis AnalitisDepartment of Hygiene, Epidemiology and Medical Statistics, National and Kapodistrian University of Athens, Greece.
Alireza EntezariFaculty of Geography and Environmental Sciences, Hakim Sabzevari University, Sabzevar Khorasan Razavi, Iran.
Fatemeh MayvanehFaculty of Geography and Environmental Sciences, Hakim Sabzevari University, Sabzevar Khorasan Razavi, Iran.
Patrick GoodmanTechnological University Dublin, Ireland.
Ariana ZekaInstitute for the Environment, Brunel University London, London, United Kingdom.
Paola MichelozziDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Francesca de'DonatoDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Barrak AlahmadDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.
Magali Hurtado DiazDepartment of Environmental Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
César De la Cruz ValenciaDepartment of Environmental Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
Ala OvercencoNational Agency for Public Health of the Ministry of Health, Labour and Social Protection of the Republic of Moldova.
Danny HouthuijsNational Institute for Public Health and the Environment (RIVM), Centre for Sustainability and Environmental Health, Bilthoven, The Netherlands.
Caroline AmelingNational Institute for Public Health and the Environment (RIVM), Centre for Sustainability and Environmental Health, Bilthoven, The Netherlands.
Shilpa RaoNorwegian institute of Public Health, Oslo, Norway.
Francesco Di RuscioNorwegian institute of Public Health, Oslo, Norway.
Gabriel CarrascoInstitute of Tropical Medicine "Alexander von Humboldt", Universidad Peruana Cayetano Heredia, Lima, Peru.
Xerxes SeposoSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki.
Baltazar NunesDepartment of Epidemiology, Instituto Nacional de Saúde Dr Ricardo, Lisboa.
Joana MadureiraDepartment of Epidemiology, Instituto Nacional de Saúde Dr Ricardo, Lisboa.
Iulian-Horia HolobacaFaculty of Geography, Babes-Bolay University, Cluj-Napoca, Romania.
Noah ScovronickGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta.
Fiorella AcquaottaDepartment of Earth Sciences, University of Torino, Torino, Italy.
Bertil ForsbergDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Christofer ÅströmDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Martina S RagettliSwiss Tropical and Public Health Institute.
Yue-Liang Leon GuoEnvironmental and Occupational Medicine, and Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University (NTU) and NTU Hospital, Taipei.
Bing-Yu ChenNational Institute of Environmental Health Science, National Health Research Institutes, Zhunan, Taiwan.
Shanshan LiDepartment of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne.
Valentina ColistroDepartment of Quantitative Methods, School of Medicine, University of the Republic, Montevideo, Uruguay.
Antonella ZanobettiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.
Joel SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.
Do Van DungDepartment of Environmental Health, Faculty of Public Health, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Ben ArmstrongDepartment of Public Health Environments and Society.
Antonio GasparriniDepartment of Public Health Environments and Society.

Funding

Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI Carmen Joseph Marsit · 2013 to 2026
$22.6M
Medical Research Council MR/R013349/1NIEHS NIH HHS P30 ES019776
6 · The paper itself

Abstract

backgroundMinimum mortality temperature (MMT) is an important indicator to assess the temperature-mortality association, indicating long-term adaptation to local climate. Limited evidence about the geographical variability of the MMT is available at a global scale.

methodsWe collected data from 658 communities in 43 countries under different climates. We estimated temperature-mortality associations to derive the MMT for each community using Poisson regression with distributed lag nonlinear models. We investigated the variation in MMT by climatic zone using a mixed-effects meta-analysis and explored the association with climatic and socioeconomic indicators.

resultsThe geographical distribution of MMTs varied considerably by country between 14.2 and 31.1 °C decreasing by latitude. For climatic zones, the MMTs increased from alpine (13.0 °C) to continental (19.3 °C), temperate (21.7 °C), arid (24.5 °C), and tropical (26.5 °C). The MMT percentiles (MMTPs) corresponding to the MMTs decreased from temperate (79.5th) to continental (75.4th), arid (68.0th), tropical (58.5th), and alpine (41.4th). The MMTs indreased by 0.8 °C for a 1 °C rise in a community's annual mean temperature, and by 1 °C for a 1 °C rise in its SD. While the MMTP decreased by 0.3 centile points for a 1 °C rise in a community's annual mean temperature and by 1.3 for a 1 °C rise in its SD.

conclusionsThe geographical distribution of the MMTs and MMTPs is driven mainly by the mean annual temperature, which seems to be a valuable indicator of overall adaptation across populations. Our results suggest that populations have adapted to the average temperature, although there is still more room for adaptation.

Indexed as

AdaptationClimateDistributed lag nonlinear modelsMinimum mortality temperatureMulti-cityMulti-countryTime-series

Identifiers

PMID34934890
PMCPMC8683148

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.