Evidence map›Paper›PMID 34934887›Full record

ArticleEnvironmental epidemiology (Philadelphia, Pa.)2021

Outdoor air pollution and anti-Müllerian hormone concentrations in the Sister Study.

Allyson M Gregoire, Kristen Upson, Nicole M Niehoff, Helen B Chin, Joel D Kaufman, Clarice R Weinberg, Dale P Sandler, Hazel B Nichols, Alexandra J White

Open access · goldAbstract read
In one paragraph

Article in Environmental epidemiology (Philadelphia, Pa.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Anti-Müllerian hormone and somatic ovarian function: a new perspective.Journal of assisted reproduction and genetics · 2026
    Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Allyson M GregoireEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC.
Kristen UpsonDepartment of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI.
Nicole M NiehoffEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC.
Helen B ChinDepartment of Global and Community Health, College of Health and Human Services, George Mason University, Fairfax, VA.
Joel D KaufmanDepartments of Environmental and Occupational Health Sciences, Medicine, and Epidemiology, University of Washington, Seattle, WA.
Clarice R WeinbergBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, NC.
Dale P SandlerEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC.
Hazel B NicholsDepartment of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC.
Alexandra J WhiteEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC.
National Institute of Environmental Health Sciences · USData Management (Italy) · ITFederal Reserve · USMichigan State University · USUniversity of North Carolina at Chapel Hill · US

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Sheela Sathyanarayana · 1995 to 2026
$42.5M
Genetic and Environmental Risk Factors for Breast Cancer: The Sister StudyZ01ES044005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 1999 to 2008
$1.3M
Intramural NIH HHS Z01 ES044005NIEHS NIH HHS P30 ES007033
6 · The paper itself

Abstract

backgroundAnti-Müllerian hormone (AMH) concentrations are a marker of ovarian reserve and are indicative of a woman's reproductive lifespan. Exposure to tobacco smoke has been associated with lower AMH concentrations; however, less is known about the association between ambient air pollution and ovarian reserve.

methodsFor 883 premenopausal Sister Study participants recruited between 2003 and 2009 in the United States, adult residential annual average concentrations of PM

resultsOverall, we observed little to no evidence of associations between AMH and air pollution concentrations or proximity to roadways. Women in the highest quartile of NO

conclusionsWe saw little consistent evidence to support an association between outdoor air pollution and diminished ovarian reserve in US women ages 35-54.

Indexed as

air pollutionanti-Müllerian hormonecohort studiesovarian reservetraffic-related air pollutants

Identifiers

PMID34934887
PMCPMC8683141
OpenAlexW4200485235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.