Evidence map›Paper›PMID 34934806›Full record

ArticleTransplantation direct2022

Patient and Clinician Perceptions of Informed Consent and Decision Making About Accepting KDPI > 85 Kidneys.

Karolina Schantz, Elisa J Gordon, Unsun Lee, Maria Rocha, John Friedewald, Daniela P Ladner, Yolanda Becker, Richard Formica, Peter P Reese, Dixon Kaufman and 5 more

Open access · goldAbstract read
In one paragraph

Article in Transplantation direct, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. The Individual Impact of Machine Perfusion on Liver and Kidney on Donor Expansion in Simultaneous Liver and Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  4. Article
  5. Article
  6. Kidney organ allocation: reducing discards.Current opinion in organ transplantation · 2023
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Karolina SchantzMcCormick School of Engineering, Department of Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL.
Elisa J GordonFeinberg School of Medicine, Northwestern University, Chicago, IL.
Unsun LeeMcCormick School of Engineering, Department of Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL.
Maria RochaWeinberg School of Arts and Sciences, Northwestern University, Evanston, IL.
John FriedewaldFeinberg School of Medicine, Northwestern University, Chicago, IL.
Daniela P LadnerFeinberg School of Medicine, Northwestern University, Chicago, IL.
Yolanda BeckerPritzker School of Medicine, University of Chicago, Chicago, IL.
Richard FormicaYale School of Medicine, Yale University, New Haven, CT.
Peter P ReesePerelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Dixon KaufmanUniversity of Wisconsin School of Medicine and Public Health, University of Wisconsin, Madison, WI.
Masoud BarahMcCormick School of Engineering, Department of Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL.
Marissa WalkerMcCormick School of Engineering, Department of Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL.
Om MehrotraCollege of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL.
Dania ViverosCollege of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL.
Sanjay MehrotraMcCormick School of Engineering, Department of Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL.
Northwestern University · USUniversity of Illinois Chicago · USUniversity of Chicago · USUniversity of Pennsylvania · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Rescuing Kidneys at Risk of DiscardR01DK118425 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MEHROTRA, SANJAY · 2019 to 2022
$2.8M
NCATS NIH HHS UL1 TR001422NCATS NIH HHS UL1 TR001863NIDDK NIH HHS R01 DK118425
6 · The paper itself

Abstract

backgroundAlthough the impact of the kidney donor profile index (KDPI) on kidney discard is well researched, less is known about how patients make decisions about whether to give consent for KDPI > 85 kidney offers.

methodsWe conducted in-depth, semistructured interviews with 16 transplant recipients, 15 transplant candidates, and 23 clinicians (transplant surgeons, nephrologists, and nurse coordinators) to assess and compare perceptions of transplant education, informed consent for KDPI > 85 kidneys' and the decision-making process for accepting kidney offers. Thematic analysis was used to analyze qualitative data.

resultsFour themes emerged: (1) patients reported uncertainty about the meaning of KDPI or could not recall information about KDPI; (2) patients reported uncertainty about their KDPI > 85 consent status and a limited role in KDPI > 85 consent decision making; (3) patients' reported willingness to consider KDPI > 85 kidneys depended on their age, health status, and experiences with dialysis, and thus it changed over time; (4) patients' underestimated the survival benefit of transplantation compared with dialysis, which could affect their KDPI > 85 consent decision making.

conclusionsTo better support patients' informed decision making about accepting KDPI > 85 kidneys, centers must ensure that all patients receive education about the trade-offs between accepting a KDPI > 85 kidney and remaining on dialysis. Additionally, education about KDPI and discussions about informed consent for KDPI > 85 kidneys must be repeated at multiple time points while patients are on the waiting list.

Identifiers

PMID34934806
PMCPMC8683202
OpenAlexW4200062220

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.