Evidence map›Paper›PMID 34934771›Full record

ArticleBioMed research international2021

Ginsenoside CK Inhibits TGF-

Mingyang Sun, Xuefeng Zhuang, Guangfu Lv, Zhe Lin, Xiaowei Huang, Jiarui Zhao, He Lin, Yuchen Wang

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mingyang SunDepartment of Pharmacology, School of Pharmaceutical Sciences, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China.ORCID https://orcid.org/0000-0001-5075-1361
Xuefeng ZhuangDepartment of Pharmacology, School of Pharmaceutical Sciences, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China.ORCID https://orcid.org/0000-0002-6768-7463
Guangfu LvDepartment of Pharmacology, School of Pharmaceutical Sciences, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China.ORCID https://orcid.org/0000-0002-6331-6139
Zhe LinDepartment of Pharmacology, School of Pharmaceutical Sciences, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China.ORCID https://orcid.org/0000-0002-4593-3897
Xiaowei HuangDepartment of Pharmacology, School of Pharmaceutical Sciences, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China.ORCID https://orcid.org/0000-0002-3120-540X
Jiarui ZhaoDepartment of Pharmacology, School of Pharmaceutical Sciences, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China.ORCID https://orcid.org/0000-0003-1240-3811
He LinDepartment of Pharmacology, School of Pharmaceutical Sciences, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China.ORCID https://orcid.org/0000-0003-3599-4837
Yuchen WangDepartment of Pharmacology, School of Pharmaceutical Sciences, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China.ORCID https://orcid.org/0000-0002-6064-9480
Changchun University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ginsenoside CK is the main metabolite of protopanaxadiol saponins in intestinal bacteria. Previous studies have shown that ginsenoside CK can affect many aspects of tumor development through a variety of mechanisms. However, few studies have reported the antimetastatic effects of ginsenoside CK in non-small-cell lung cancer (NSCLC). In this study, we explored the effect of ginsenoside CK on epithelial-mesenchymal transition (EMT) induced by TGF-

Indexed as

A549 CellsAnimalsCadherinsCell Line, TumorCell MovementDown-RegulationEpithelial-Mesenchymal TransitionGinsenosidesHumansLung NeoplasmsMaleMiceMice, Inbred BALB CMice, NudeSirtuin 1Transforming Growth Factor betaCadherinsginsenoside compound KGinsenosidesSIRT1 protein, humanSirtuin 1Transforming Growth Factor betaVimentin

Identifiers

PMID34934771
PMCPMC8684819
OpenAlexW4200410922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.