Evidence map›Paper›PMID 34934721›Full record

ArticleIndian dermatology online journal

Pediatric Cutaneous Leishmaniasis: A Clinico-Epidemiological Study from North India.

Shagufta Rather, Atiya Yaseen, Faizan Younus Shah, Mashkoor Wani, Kewal Krishan, Sumaya Zirak, Rajesh Sharma, Iffat Hassan, Devraj Dogra, Ruby Rishi

Open access · diamondAbstract read
In one paragraph

Article in Indian dermatology online journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Visceral Leishmaniasis in Sub-Himalayan India (1967-2023): A Systematic Review.The American journal of tropical medicine and hygiene · 2024
    Pooled it
  2. Article
  3. Review
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  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Shagufta RatherDepartment of Dermatology, Government Medical College, Srinagar, Kashmir University, Jammu and Kashmir, India.
Atiya YaseenDepartment of Dermatology, Government Medical College, Srinagar, Kashmir University, Jammu and Kashmir, India.
Faizan Younus ShahDepartment of Dermatology, Government Medical College, Srinagar, Kashmir University, Jammu and Kashmir, India.
Mashkoor WaniDepartment of Dermatology, Government Medical College, Jammu University. Jammu and Kashmir, India.
Kewal KrishanDepartment of Dermatology, Government Medical College, Srinagar, Kashmir University, Jammu and Kashmir, India.
Sumaya ZirakDepartment of Dermatology, Government Medical College, Srinagar, Kashmir University, Jammu and Kashmir, India.
Rajesh SharmaDepartment of Dermatology, Government Medical College, Jammu University. Jammu and Kashmir, India.
Iffat HassanDepartment of Dermatology, Government Medical College, Srinagar, Kashmir University, Jammu and Kashmir, India.
Devraj DograDepartment of Dermatology, Government Medical College, Jammu University. Jammu and Kashmir, India.
Ruby RishiDepartment of Pathology, Government Medical College, Srinagar, Kashmir University, Jammu and Kashmir, India.
Government Medical College · INGovernment Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere has been an upsurge in the cases of cutaneous leishmaniasis over the past few years in the pediatric population of Jammu and Kashmir, hitherto a nonendemic area for the disease., The aim of this study was to describe the clinico-epidemiological profile and therapeutic outcome of pediatric cutaneous leishmaniasis (PCL) over a 10-year period in J and K. MATERIALS AND

methodsAn observational study was conducted at two tertiary care hospitals of Jammu and Kashmir over a period of 10 years (July 2010-June 20). Children presenting to the outpatient department with lesions suggestive of CL were enrolled. Patients suspected of having CL based on clinical criteria were subjected to slit skin smears (SSS) and histopathological examination (HPE) for validation of the diagnosis. Intralesional or systemic sodium stibogluconate (SSG) was the treatment modality used for the management of patients. Clinical follow-up was done at intervals of 2 weeks for the first 2 months and monthly thereafter.

resultsA total of 376 cases of CL in children aged 1.5-15 years (mean age 8.4 ± 1.4 years) were included in the study. The duration of the disease ranged from 8 to 52 weeks (mean 22.52 ± 1.5 weeks). Lesions were noted mainly on exposed parts of the body, with face being the most commonly affected site (89.0%). Nodulo-ulcerative plaques were the predominant clinical presentation (62.76%). The diagnosis was confirmed by the demonstration of Leishman Donovan (LD) bodies in 54.25% on SSS- and 25.79% on hematoxylin and eosin -stained tissue sections. In cases where diagnosis could not be confirmed by demonstration of LD body, a histological pattern conforming to CL and response to a therapeutic trial of SSG provided evidence of leishmanial infection. Complete healing was achieved in 95.02% of the cases at the end of treatment.

conclusionCL is an emerging health problem in the pediatric population of Jammu and Kashmir. Awareness among pediatric health workers regarding this disease and recognition among the differential diagnosis of ulcerated papules or plaques in the pediatric population is imperative.

Indexed as

Cutaneous leishmaniasisintralesionalJammu and KashmirLD bodiesnon-endemicpediatricsodium stibogluconate

Identifiers

PMID34934721
PMCPMC8653750
OpenAlexW3216662520

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.