Evidence map›Paper›PMID 34934522›Full record

ArticleJournal of pathology informatics2021

Programmed Cell Death Ligand 1 Pathologist Training in the Time of COVID-19: Our Experience using a Digital Solution.

Dorothy Hayden, Joseph M Herndon, James C Campion, Janine D Feng, Fangru Lian, Jessica L Baumann, Bryan K Roland, Ehab A ElGabry

Abstract read
In one paragraph

Article in Journal of pathology informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dorothy HaydenCompanion Diagnostics Pathology, Roche Tissue Diagnostics, Tucson, AZ, USA.
Joseph M HerndonAssay and Reagent Development, Roche Tissue Diagnostics, Tucson, AZ, USA.
James C CampionResearch and Development Information Technology, Roche Tissue Diagnostics, Tucson, AZ, USA.
Janine D FengCompanion Diagnostics Pathology, Roche Tissue Diagnostics, Tucson, AZ, USA.
Fangru LianCompanion Diagnostics Pathology, Roche Tissue Diagnostics, Tucson, AZ, USA.
Jessica L BaumannCompanion Diagnostics Pathology, Roche Tissue Diagnostics, Tucson, AZ, USA.
Bryan K RolandCompanion Diagnostics Project Leadership, Roche Tissue Diagnostics, Tucson, AZ, USA.
Ehab A ElGabryCompanion Diagnostics Pathology, Roche Tissue Diagnostics, Tucson, AZ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic presented numerous challenges to the continuity of programmed cell death ligand 1 (PD-L1) assay training events conducted by our organization. Under typical conditions, these training events are face-to-face affairs, where participants are trained to assay algorithms on glass slides during multi-headed scope sessions. Social distancing measures undertaken to slow pandemic spread necessitated the adaptation of our training methods to facilitate assay training and subsequent continuation of clinical trials. The present report details the creation and use of the Roche pathology training portal (PTP) that allowed for remote training to diagnostic assay algorithms. The PTP is a web-based system comprised of a learning management system (LMS) coupled to an image management system (IMS). Whole slide images (WSIs) were produced using a DP200 instrument (Roche, Pleasanton, CA) and these scan files were then uploaded to an IMS. Courses were created on the LMS using annotated WSIs that were shared with enrolled pathologists worldwide during assay training events. These courses culminated in assay certification examinations, where pathologists evaluated test-case WSIs and evaluated these cases within the LMS. Trainee submissions were analyzed for pass/fail status by comparing user data entries with consensus scores on these test-case WSIs. To date, 47 pathologist trainings have occurred and of these, 44 have successfully passed the associated assay certification exam on the first attempt (93% 1

Indexed as

COVIDdiagnosticdigital pathologyprogrammed cell death ligand 1trainingwhole slide images

Identifiers

PMID34934522
PMCPMC8652342

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.