Evidence map›Paper›PMID 34934508›Full record

ArticleRespirology case reports2022

Recurrent COVID-19 infection in a case of rituximab-induced hypogammaglobulinaemia.

Jefferson Daniel, Balamugesh Thangakunam, Barney Thomas Jesudason Isaac, Mahesh Moorthy, Devasahayam Jesudas Christopher

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respirology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jefferson DanielDepartment of Pulmonary Medicine Christian Medical College Vellore India.ORCID https://orcid.org/0000-0003-4285-7910
Balamugesh ThangakunamDepartment of Pulmonary Medicine Christian Medical College Vellore India.ORCID https://orcid.org/0000-0001-6799-065X
Barney Thomas Jesudason IsaacDepartment of Pulmonary Medicine Christian Medical College Vellore India.ORCID https://orcid.org/0000-0003-3515-7510
Mahesh MoorthyDepartment of Clinical Virology Christian Medical College Vellore India.ORCID https://orcid.org/0000-0001-6040-040X
Devasahayam Jesudas ChristopherDepartment of Pulmonary Medicine Christian Medical College Vellore India.ORCID https://orcid.org/0000-0002-9405-8494
Christian Medical College, Vellore · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with immunodeficiency are at an increased risk of recurrent COVID-19 infection. They may lack the natural immune response that usually confers long-lasting immunity. Here, we present our experience managing one such patient, who had a COVID-19 infection twice, 5 months apart. He had a positive SARS-CoV-2 real-time reverse transcription polymerase chain reaction (RT-PCR) and computed tomography (CT) thorax with classical findings of COVID-19 on both occasions. He had multiple negative RT-PCR tests and two CT scans without COVID-19 features between these two infections. While the antibody response to the first infection was not detectable, the response to the second infection was robust. Live attenuated vaccines are contraindicated in patients with immunodeficiency, and other vaccines may not elicit an adequate immune response. A high index of suspicion for recurrent COVID-19 is warranted in this group of patients.

Indexed as

COVID‐19hypogammaglobulinaemiarecurrent COVID‐19re‐infectionrituximab

Identifiers

PMID34934508
PMCPMC8652043
OpenAlexW4200289142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.