Evidence map›Paper›PMID 34934327›Full record

ReviewJournal of asthma and allergy2021

Oral Immunotherapy in Children: Clinical Considerations and Practical Management.

Brent Anderson, Lauren Wong, Bahman Adlou, Andrew Long, R Sharon Chinthrajah

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of asthma and allergy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Brent AndersonSean N Parker Center for Allergy and Asthma Research at Stanford University, Stanford University, Stanford, CA, USA.
Lauren WongSean N Parker Center for Allergy and Asthma Research at Stanford University, Stanford University, Stanford, CA, USA.
Bahman AdlouSean N Parker Center for Allergy and Asthma Research at Stanford University, Stanford University, Stanford, CA, USA.
Andrew LongSean N Parker Center for Allergy and Asthma Research at Stanford University, Stanford University, Stanford, CA, USA.
R Sharon ChinthrajahSean N Parker Center for Allergy and Asthma Research at Stanford University, Stanford University, Stanford, CA, USA.ORCID 0000-0003-2467-4256
Stanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral immunotherapy (OIT) in pediatric patients provides an alternative option to the current standard of care in food allergy, which is allergen avoidance and reactive treatment. Because patients are exposed to one or more food allergens during treatment, OIT is associated with adverse events and can be a cumbersome process for children, their caregivers, and clinicians. However, there have been an overwhelming number of studies that show high efficacy in both single- and multi-allergen OIT, and that quality of life is greatly improved for both patients and their families after undergoing immunotherapy. This review discusses clinical considerations for OIT in pediatrics, including efficacy and safety, practical management, and future directions of treatment.

Indexed as

atopydesensitizationdupilumabfood allergyIgEomalizumabsustained unresponsivenesstolerance

Identifiers

PMID34934327
PMCPMC8684389
OpenAlexW4200230471

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.