Evidence map›Paper›PMID 34934098›Full record

ArticleScientific reports2021

Antimicrobial efficacy of Egyptian Eremina desertorum and Helix aspersa snail mucus with a novel approach to their anti-inflammatory and wound healing potencies.

Nessma A El-Zawawy, Mahy M Mona

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Integrating in vivo and in silico: a comprehensive study of Helix aspersa mucin's therapeutic properties.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  3. Article
  4. Diet-Dependent Chemical Profiling and Bioactivity ofMolecules (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Chemical Variability and Biological Potential ofMolecules (Basel, Switzerland) · 2025
    Review
  9. Article
  10. Unveiling the therapeutic journey of snail mucus in diabetic wound care.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  11. Synergistic Antibacterial Effect of Mucus Fraction fromAntibiotics (Basel, Switzerland) · 2025
    Article
  12. Review
  13. Fabrication of BioactiveACS omega · 2024
    Article
  14. Article
  15. Heliyon · 2024
    Article
  16. Biological Properties of the Mucus and Eggs ofInternational journal of molecular sciences · 2024
    Article
  17. Review
  18. Review
  19. Heliyon · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nessma A El-ZawawyBotany Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt. nesma.elzawawi@science.tanta.edu.eg.
Mahy M MonaZoology Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt.
Tanta University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Snail mucus is composed of bioactive compounds thought to have different biological properties for the treatment of some skin problems. Although Helix aspersa mucus is used in several cosmetic products, a detailed characterization of Eremina desertorum mucus composition and its biological activities is still missing. Mucus extracts (MEs) from H. aspersa and E. desertorum were prepared and tested for their antimicrobial and anti-inflammatory activities with their potencies in wound healing. Also, chemical characterization was performed by GC-MS analysis. Results showed that ME of E. desertorum gave higher inhibitory activity against resistant strains related to burn wound infections compared to ME of H. aspersa. Additionally, it revealed a significant anti-inflammatory activity. Moreover, we found that ME of E. desertorum lacked cytotoxicity and was able to significantly induce cell proliferation and migration through up-regulation of TGF-β1 and VEGF gene expression. Our results suggested that MEs of E. desertorum have higher biological effects than H. aspersa, which are attributable to antimicrobial, anti-inflammatory activities, cell proliferation and pave the way for further investigating its potential effect as a human therapeutic agent.

Indexed as

Wound HealingAnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsBacteriaHelix, SnailsHumansMucusSkinTissue ExtractsAnti-Bacterial AgentsAnti-Inflammatory AgentsTissue Extracts

Identifiers

PMID34934098
PMCPMC8692597
OpenAlexW4200334538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.