Evidence map›Paper›PMID 34934047›Full record

ArticleNature communications2021

The genomes of 204 Vitis vinifera accessions reveal the origin of European wine grapes.

Gabriele Magris, Irena Jurman, Alice Fornasiero, Eleonora Paparelli, Rachel Schwope, Fabio Marroni, Gabriele Di Gaspero, Michele Morgante

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
18.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 91 citations in OpenAlex.

  1. Article
  2. A Metabolome Atlas of Grape Biodiversity.Journal of agricultural and food chemistry · 2026
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  4. The dynamics of introgression and parallel adaptation across North AmericanProceedings of the National Academy of Sciences of the United States of America · 2026
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  17. Grape ripening speed slowed down using natural variation.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Gabriele MagrisDepartment of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Udine, Italy.
Irena JurmanIstituto di Genomica Applicata, Udine, Italy.
Alice FornasieroDepartment of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Udine, Italy.ORCID http://orcid.org/0000-0001-6165-4233
Eleonora PaparelliDepartment of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Udine, Italy.
Rachel SchwopeDepartment of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Udine, Italy.
Fabio MarroniDepartment of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Udine, Italy.ORCID http://orcid.org/0000-0002-1556-5907
Gabriele Di GasperoIstituto di Genomica Applicata, Udine, Italy. digaspero@appliedgenomics.org.ORCID http://orcid.org/0000-0001-5810-2163
Michele MorganteDepartment of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Udine, Italy. michele.morgante@uniud.it.ORCID http://orcid.org/0000-0003-2591-2156
University of Udine · ITIstituto di Genomica Applicata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to elucidate the still controversial processes that originated European wine grapes from its wild progenitor, here we analyse 204 genomes of Vitis vinifera and show that all analyses support a single domestication event that occurred in Western Asia and was followed by numerous and pervasive introgressions from European wild populations. This admixture generated the so-called international wine grapes that have diffused from Alpine countries worldwide. Across Europe, marked differences in genomic diversity are observed in local varieties that are traditionally cultivated in different wine producing countries, with Italy and France showing the largest diversity. Three genomic regions of reduced genetic diversity are observed, presumably as a consequence of artificial selection. In the lowest diversity region, two candidate genes that gained berry-specific expression in domesticated varieties may contribute to the change in berry size and morphology that makes the fruit attractive for human consumption and adapted for winemaking.

Indexed as

Genome, PlantEuropeFruitGenetic VariationPhenotypeVitisWine

Identifiers

PMID34934047
PMCPMC8692429
OpenAlexW4200299432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.