Evidence map›Paper›PMID 34933819›Full record

ArticleTransfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis2022

Seroprevalence of SARS-CoV-2 IgG antibody among healthy blood donors: a single centre study.

Ram Jaiswal, Shweta Sharma, Ashina Singla, Nimisha Devpura, Rajat Vohra, Munish Kakkar, Puneet Rijhwani, Rajendra Sureka

Open access · bronzeAbstract read
In one paragraph

Article in Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Seroprevalence of SARS-CoV-2 antibodies in blood donors during the third wave of infection in Campeche Mexico.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2022
    Article
  3. Observational
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ram JaiswalDept. of Transfusion Medicine, Mahatma Gandhi Medical College & Hospital, Jaipur, India. Electronic address: drrmjaiswal@mgumst.org.
Shweta SharmaDept. of Transfusion Medicine, Mahatma Gandhi Medical College & Hospital, Jaipur, India.
Ashina SinglaDept. of Microbiology, Mahatma Gandhi Medical College & Hospital, Jaipur, India.
Nimisha DevpuraDept. of Pathology, Mahatma Gandhi Medical College & Hospital, Jaipur, India.
Rajat VohraDept. of Community Medicine, Mahatma Gandhi Medical College & Hospital, Jaipur, India.
Munish KakkarDept. of Pediatrics, Mahatma Gandhi Medical College & Hospital, Jaipur, India.
Puneet RijhwaniDept. of General Medicine, Mahatma Gandhi Medical College & Hospital, Jaipur, India.
Rajendra SurekaDept. of Neurology, Mahatma Gandhi Medical College & Hospital, Jaipur, India.
Gandhi Medical College & Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere acute respiratory syndrome corona virus 2(SARS-CoV-2), the causative agent of corona virus disease-2019(COVID- 19) which has led to a global pandemic. The true extent of the burden of COVID-19 may be underestimated, and there is need to know the current prevalence of SARS-CoV-2 antibody in population.

methodsThe present study was a cross-sectional study to assess prevalence of SARS-CoV- 2 IgG antibody among 586 healthy voluntary blood donors who donated whole blood between mid-December 2020 to January 2021. A chemiluminescence assay was used to detect the presence of SARS-CoV-2 IgG antibody in serum samples in addition to recommended transfusion transmitted infections tests and Signal to Cut Off (S/C) > 1 was considered as reactive for antibody as per manufacturer's instructions.

resultsIn the present study, 586 healthy voluntary blood donors were enrolled and were screened for SARS- CoV-2 IgG antibody. Out of 586 donors, 52 donors had indeterminate values of SARS-CoV-2 IgG antibody. A total of 534 healthy voluntary blood donors' samples were included in the present study for analysis. Out of total 534 healthy blood donors, 42.88% (229) were found to be seropositive while 57.11% (305) were found to be seronegative.

conclusionA 43% positivity of SARS-CoV-2 IgG antibody among healthy blood donors was detected which is an indication of presence of infection at community level and majority of the population already has been exposed to SARS-CoV-2 infection. However, there was no statistically significant association of type of blood group and age with seropositivity.

Indexed as

COVID-19SARS-CoV-2Antibodies, ViralBlood DonorsCross-Sectional StudiesHumansImmunoglobulin GSeroepidemiologic StudiesAntibodies, ViralImmunoglobulin GBlood donorsBlood GroupSARS-CoV-2 IgG antibodySeroprevalence

Identifiers

PMID34933819
PMCPMC8645505
OpenAlexW4200281791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.