Evidence map›Paper›PMID 34933392›Full record

ArticleRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2021

High-Grade Transformation in Adenoid Cystic Carcinoma of the Bartholin Gland: Case Report.

Aline Evangelista Santiago, Nicky Teunissen, Bernardo Ferreira de Paula Ricardo, Eduardo Batista Cândido, Rafaela de Souza Furtado, Agnaldo Lopes da Silva Filho

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Aline Evangelista SantiagoGynecology Department, Universidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, SP, Brazil.ORCID 0000-0002-4562-3784
Nicky TeunissenGynecology Department, Univeridade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID 0000-0002-5036-3702
Bernardo Ferreira de Paula RicardoPathology Department, Hospital MaterDei, Belo Horizonte, MG, Brazil.ORCID 0000-0002-1891-1457
Eduardo Batista CândidoGynecology Department, Univeridade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID 0000-0002-2336-5999
Rafaela de Souza FurtadoGynecology Department, Univeridade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID 0000-0002-2903-7232
Agnaldo Lopes da Silva FilhoGynecology Department, Universidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, SP, Brazil.ORCID 0000-0002-8486-7861
Universidade Federal de Minas Gerais · BRMater Dei Hospital · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn the present study, we report a case of primary adenoid cystic carcinoma (ACC) of the Bartholin gland with high-grade transformation (HGT). Adenoid cystic carcinoma of the Bartholin gland is a rare tumor and HGT has only been reported in head and neck tumors. CASE REPORT: A 77-year-old woman with a non-ulcerated vulvar lesion on the topography of the right Bartholin gland. The patient was submitted to tumor resection followed by V-Y island flap and adjuvant radiotherapy. The histopathological examination revealed primary ACC of the Bartholin gland, with areas of HGT and extensive perineural invasion. The immunohistochemical study with p53 showed a diffuse and strong positive reaction in areas with HGT. After 24 months of follow-up, the patient presented distant metastases and died, despite having undergone to chemotherapy.

conclusionAs far as we know, this case is the first description in the literature of HGT in ACC of the Bartholin gland, and HGT appears to be associated with tumor aggressiveness.

Indexed as

Bartholin's GlandsCarcinoma, Adenoid CysticVulvar NeoplasmsAgedFemaleHumansRadiotherapy, Adjuvant

Identifiers

PMID34933392
PMCPMC10183931
OpenAlexW4200294196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.