Evidence map›Paper›PMID 34933049›Full record

ArticleNeuropharmacology2022

Independent of differences in taste, B6N mice consume less alcohol than genetically similar B6J mice, and exhibit opposite polarity modulation of tonic GABA

Chloe M Erikson, Kevin T Douglas, Talia O Thuet, Ben D Richardson, Claudia Mohr, Hiroko Shiina, Josh S Kaplan, David J Rossi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuropharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Chloe M EriksonDepartment of Integrative Physiology and Neuroscience, 1815 Ferdinands Lane, Washington State University, Pullman, WA, 99164-7620, USA.
Kevin T DouglasDepartment of Integrative Physiology and Neuroscience, 1815 Ferdinands Lane, Washington State University, Pullman, WA, 99164-7620, USA.
Talia O ThuetDepartment of Integrative Physiology and Neuroscience, 1815 Ferdinands Lane, Washington State University, Pullman, WA, 99164-7620, USA.
Ben D RichardsonDepartment of Integrative Physiology and Neuroscience, 1815 Ferdinands Lane, Washington State University, Pullman, WA, 99164-7620, USA; Department of Pharmacology, Southern Illinois University - School of Medicine, Springfield, IL, USA.
Claudia MohrDepartment of Integrative Physiology and Neuroscience, 1815 Ferdinands Lane, Washington State University, Pullman, WA, 99164-7620, USA.
Hiroko ShiinaDepartment of Integrative Physiology and Neuroscience, 1815 Ferdinands Lane, Washington State University, Pullman, WA, 99164-7620, USA; Department of Physiology, University College London, London, UK.
Josh S KaplanDepartment of Psychology, Western Washington University, Bellinham, WA, 9822, USA; Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, USA.
David J RossiDepartment of Integrative Physiology and Neuroscience, 1815 Ferdinands Lane, Washington State University, Pullman, WA, 99164-7620, USA. Electronic address: david.rossi@wsu.edu.
Washington State University · USOregon Health & Science University · USSouthern Illinois University School of Medicine · USUniversity College London · GB

Funding

Cerebellar Contributions to Alcohol Use DisordersR01AA026078 · NIAAA · WASHINGTON STATE UNIVERSITY · PI ROSSI, DAVID J · 2017 to 2021
$1.7M
NIAAA NIH HHS R01 AA026078
6 · The paper itself

Abstract

Genetic differences in cerebellar sensitivity to alcohol (EtOH) influence EtOH consumption phenotype in animal models and contribute to risk for developing an alcohol use disorder in humans. We previously determined that EtOH enhances cerebellar granule cell (GC) tonic GABA

Indexed as

Cerebellar CortexElectrophysiological PhenomenaNitric Oxide Synthase Type IReceptors, GABA-AAlcohol DrinkingAlcoholismAnimalsBehavior, AnimalCentral Nervous System DepressantsDisease Models, AnimalEthanolMaleMiceMice, Inbred C57BLSpecies SpecificityCentral Nervous System DepressantsEthanolNitric Oxide Synthase Type IReceptors, GABA-AAlcohol use disorderCerebellumGABAGenetic predilectionnNOS

Identifiers

PMID34933049
PMCPMC9208337
OpenAlexW4200104948

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.