Evidence map›Paper›PMID 34933044›Full record

ArticleAntiviral research2022

COVID-19, Influenza and RSV: Surveillance-informed prevention and treatment - Meeting report from an isirv-WHO virtual conference.

Jennifer L McKimm-Breschkin, Alan J Hay, Bin Cao, Rebecca J Cox, Jake Dunning, Ann C Moen, Daniel Olson, Andrés Pizzorno, Frederick G Hayden

Open access · greenAbstract readConference Proceedings
In one paragraph

Article in Antiviral research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. First-generation oral antivirals against SARS-CoV-2.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
    Review
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 7 countries.

Jennifer L McKimm-BreschkinDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia. Electronic address: jmbvirology@gmail.com.
Alan J HayThe Francis Crick Institute, London, UK. Electronic address: alan.hay@crick.ac.uk.
Bin CaoChina-Japan Friendship Hospital, National Clinical Research Center for Respiratory Diseases, Clinical Center for Pulmonary Infections, Capital Medical University, Beijing, China. Electronic address: caobin_ben@163.com.
Rebecca J CoxInfluenza Centre, Department of Clinical Science, University of Bergen, Bergen, Norway. Electronic address: rebecca.cox@uib.no.
Jake DunningCentre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK. Electronic address: jake.dunning@ndm.ox.ac.uk.
Ann C MoenInfluenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: alc3@cdc.gov.
Daniel OlsonUniversity of Colorado School of Medicine and Colorado School of Public Health, Anschutz Medical Campus, Aurora, CO, USA. Electronic address: daniel.olson@childrenscolorado.org.
Andrés PizzornoInternational Center for Research in Infectious Diseases, University of Lyon, Lyon, France. Electronic address: mario-andres.pizzorno@univ-lyon1.fr.
Frederick G HaydenDivision of Infectious Diseases and International Health, University of Virginia School of Medicine, Charlottesville, VA, USA. Electronic address: fgh@virginia.edu.
Angkor Hospital for Children · KHCapital Medical University · CNCenters for Disease Control and Prevention · USColorado School of Public Health · USThe Francis Crick Institute · GBThe University of Melbourne · AUUniversité Claude Bernard Lyon 1 · FRUniversity of Bergen · NOUniversity of Virginia Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The International Society for Influenza and other Respiratory Virus Diseases (isirv) and the WHO held a joint virtual conference from 19th-21st October 2021. While there was a major focus on the global response to the SARS-CoV-2 pandemic, including antivirals, vaccines and surveillance strategies, papers were also presented on treatment and prevention of influenza and respiratory syncytial virus (RSV). Potential therapeutics for SARS-CoV-2 included host-targeted therapies baricitinib, a JAK inhibitor, tocilizumab, an IL-6R inhibitor, verdinexor and direct acting antivirals ensovibep, S-217622, AT-527, and monoclonal antibodies casirivimab and imdevimab, directed against the spike protein. Data from trials of nirsevimab, a monoclonal antibody with a prolonged half-life which binds to the RSV F-protein, and an Ad26.RSV pre-F vaccine were also presented. The expanded role of the WHO Global Influenza Surveillance and Response System to address the SARS-CoV-2 pandemic was also discussed. This report summarizes the oral presentations given at this meeting for the benefit of the broader medical and scientific community involved in surveillance, treatment and prevention of respiratory virus diseases.

Indexed as

COVID-19Global HealthHumansInfluenza, HumanRespiratory Syncytial Virus InfectionsWorld Health OrganizationAntiviralsInfluenzaRSVSARS-CoV-2Vaccines

Identifiers

PMID34933044
PMCPMC8684224
OpenAlexW4200459552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.