Evidence map›Paper›PMID 34932721›Full record

ReviewJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia2021

2021 Brazilian Thoracic Association recommendations for the management of severe asthma.

Regina Maria de Carvalho-Pinto, José Eduardo Delfini Cançado, Marcia Margaret Menezes Pizzichini, Jussara Fiterman, Adalberto Sperb Rubin, Alcindo Cerci Neto, Álvaro Augusto Cruz, Ana Luisa Godoy Fernandes, Ana Maria Silva Araujo, Daniela Cavalet Blanco and 7 more

Open access · diamondAbstract readReview
In one paragraph

Review in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Review
  4. Article
  5. Navigating change: the trajectory of the Jornal Brasileiro de Pneumologia in a dynamic scientific landscape and its international recognition.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Article
  6. Article
  7. Effectiveness of Intravenous and Nebulized MgSOChildren (Basel, Switzerland) · 2025
    Review
  8. Asthma-related deaths in Brazil: data from an ecological study.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Article
  9. Asthma and pregnancy.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Review
  10. Diagnosis and treatment of asthma in childhood: an overview of guidelines.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024
    Article
  11. The role of IL10 and IL17 gene polymorphisms in treatment response in children and adolescents with severe asthma.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024
    Article
  12. Article
  13. Periostin as an important biomarker of inflammatory phenotype T2 in Brazilian asthma patients.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023
    Article
  14. Asthma and pregnancy.Revista da Associacao Medica Brasileira (1992) · 2023
    Article
  15. Characteristics of individuals with moderate to severe asthma who better respond to aerobic training: a cluster analysis.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023
    Article
  16. Severe asthma phenotyping: does the definition of different phenotypes matter?Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Article
  17. Celebrating World Asthma Day in Brazil: lessons learned from the pandemic. Can we do better?Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Article
  18. Prevalence of the eosinophilic phenotype among severe asthma patients in Brazil: the BRAEOS study.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Article
  19. Severe asthma in Brazil: from diagnosis to treatment.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 15 institutions in 1 country.

Regina Maria de Carvalho-Pinto. Divisão de Pneumologia, Instituto do Coração - InCor - Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.ORCID 0000-0002-6344-2127
José Eduardo Delfini Cançado. Faculdade de Ciências Médicas, Santa Casa de Misericórdia de São Paulo, São Paulo (SP) Brasil.ORCID 0000-0003-1238-8498
Marcia Margaret Menezes Pizzichini. Programa de Pós-Graduação em Ciências Médicas, Universidade Federal de Santa Catarina - UFSC - Florianópolis (SC) Brasil.ORCID 0000-0001-7409-7536
Jussara Fiterman. Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS - Porto Alegre (RS) Brasil.ORCID 0000-0003-0916-0388
Adalberto Sperb Rubin. Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA - Porto Alegre (RS) Brasil.ORCID 0000-0002-4591-1444
Alcindo Cerci Neto. Universidade Estadual de Londrina - UEL - Londrina (PR) Brasil.ORCID 0000-0002-1702-7475
Álvaro Augusto Cruz. Universidade Federal da Bahia - UFBA - Salvador (BA) Brasil.ORCID 0000-0002-7403-3871
Ana Luisa Godoy Fernandes. Escola Paulista de Medicina, Universidade Federal de São Paulo - UNIFESP - São Paulo (SP) Brasil.ORCID 0000-0003-3910-6016
Ana Maria Silva Araujo. Instituto de Doenças do Tórax, Universidade Federal do Rio de Janeiro - IDT/UFRJ - Rio de Janeiro (RJ) Brasil.ORCID 0000-0001-8130-4572
Daniela Cavalet Blanco. Escola de Medicina, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS - Porto Alegre (RS), Brasil.ORCID 0000-0002-3125-1385
Gediel Cordeiro Junior. Hospital Júlia Kubitschek, Fundação Hospitalar do Estado de Minas Gerais - FHEMIG - Belo Horizonte (MG) Brasil.ORCID 0000-0002-2657-5481
Lilian Serrasqueiro Ballini Caetano. Escola Paulista de Medicina, Universidade Federal de São Paulo - UNIFESP - São Paulo (SP) Brasil.ORCID 0000-0003-3024-6880
Marcelo Fouad Rabahi. Faculdade de Medicina, Universidade Federal de Goiás - UFG - Goiânia (GO) Brasil.ORCID 0000-0002-4050-5906
Marcelo Bezerra de Menezes. Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto (SP) Brasil.ORCID 0000-0001-9328-0125
Maria Alenita de Oliveira. Universidade Federal da Paraíba - UFPB - João Pessoa (PB) Brasil.ORCID 0000-0002-1009-6988
Marina Andrade Lima. Hospital Dia do Pulmão, Blumenau (SC) Brasil.ORCID 0000-0002-6864-1571
Paulo Márcio Pitrez. Hospital Moinhos de Vento, Porto Alegre (RS) Brasil.ORCID 0000-0001-7319-1133
Pontifícia Universidade Católica do Rio Grande do Sul · BRUniversidade Federal de São Paulo · BRFaculdade de Ciências Médicas da Santa Casa de São Paulo · BRFundação Hospitalar do Estado de Minas Gerais · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRHospital Moinhos de Vento · BRUniversidade de Ribeirão Preto · BRUniversidade Estadual de Londrina · BRUniversidade Federal da Bahia · BRUniversidade Federal da Paraíba · BRUniversidade Federal de Ciências da Saúde de Porto Alegre · BRUniversidade Federal de Goiás · BRUniversidade Federal de Santa Catarina · BRUniversidade Federal do Rio de Janeiro · BRUniversidade Regional de Blumenau · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in the understanding that severe asthma is a complex and heterogeneous disease and in the knowledge of the pathophysiology of asthma, with the identification of different phenotypes and endotypes, have allowed new approaches for the diagnosis and characterization of the disease and have resulted in relevant changes in pharmacological management. In this context, the definition of severe asthma has been established, being differentiated from difficult-to-control asthma. These recommendations address this topic and review advances in phenotyping, use of biomarkers, and new treatments for severe asthma. Emphasis is given to topics regarding personalized management of the patient and selection of biologicals, as well as the importance of evaluating the response to treatment. These recommendations apply to adults and children with severe asthma and are targeted at physicians involved in asthma treatment. A panel of 17 Brazilian pulmonologists was invited to review recent evidence on the diagnosis and management of severe asthma, adapting it to the Brazilian reality. Each of the experts was responsible for reviewing a topic or question relevant to the topic. In a second phase, four experts discussed and structured the texts produced, and, in the last phase, all experts reviewed and approved the present manuscript and its recommendations.

Indexed as

AsthmaBiomarkersBrazilHumansPhenotypeBiomarkers

Identifiers

PMID34932721
PMCPMC8836628
OpenAlexW4206428749

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.