Evidence map›Paper›PMID 34932550›Full record

ArticlePLoS computational biology2021

SWIFT: A deep learning approach to prediction of hypoxemic events in critically-Ill patients using SpO2 waveform prediction.

Akshaya V Annapragada, Joseph L Greenstein, Sanjukta N Bose, Bradford D Winters, Sridevi V Sarma, Raimond L Winslow

Abstract read
In one paragraph

Article in PLoS computational biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Akshaya V AnnapragadaJohns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.ORCID 0000-0002-9097-6511
Joseph L GreensteinInstitute for Computational Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America.ORCID 0000-0002-6193-7134
Sanjukta N BoseInstitute for Computational Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America.ORCID 0000-0003-1077-4010
Bradford D WintersAnesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.ORCID 0000-0002-5190-6481
Sridevi V SarmaInstitute for Computational Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America.
Raimond L WinslowInstitute for Computational Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America.ORCID 0000-0003-1719-1651

Funding

Medical Scientist Training ProgramT32GM136577 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ANDREA L COX · 2020 to 2026
$13.4M
NIGMS NIH HHS T32 GM136577
6 · The paper itself

Abstract

Hypoxemia is a significant driver of mortality and poor clinical outcomes in conditions such as brain injury and cardiac arrest in critically ill patients, including COVID-19 patients. Given the host of negative clinical outcomes attributed to hypoxemia, identifying patients likely to experience hypoxemia would offer valuable opportunities for early and thus more effective intervention. We present SWIFT (SpO2 Waveform ICU Forecasting Technique), a deep learning model that predicts blood oxygen saturation (SpO2) waveforms 5 and 30 minutes in the future using only prior SpO2 values as inputs. When tested on novel data, SWIFT predicts more than 80% and 60% of hypoxemic events in critically ill and COVID-19 patients, respectively. SWIFT also predicts SpO2 waveforms with average MSE below .0007. SWIFT predicts both occurrence and magnitude of potential hypoxemic events 30 minutes in the future, allowing it to be used to inform clinical interventions, patient triaging, and optimal resource allocation. SWIFT may be used in clinical decision support systems to inform the management of critically ill patients during the COVID-19 pandemic and beyond.

Indexed as

Critical IllnessDeep LearningOxygen SaturationCOVID-19HumansHypoxiaIntensive Care UnitsPandemicsSARS-CoV-2

Identifiers

PMID34932550
PMCPMC8730462

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.