Evidence map›Paper›PMID 34932407›Full record

ArticlePsychological science2022

Frequent Interpersonal Stress and Inflammatory Reactivity Predict Depressive-Symptom Increases: Two Tests of the Social-Signal-Transduction Theory of Depression.

Annelise A Madison, Rebecca Andridge, M Rosie Shrout, Megan E Renna, Jeanette M Bennett, Lisa M Jaremka, Christopher P Fagundes, Martha A Belury, William B Malarkey, Janice K Kiecolt-Glaser

Open access · greenAbstract read
In one paragraph

Article in Psychological science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Omega-3 fatty acids reduce depressive symptoms only among the socially stressed: A corollary of the social signal transduction theory of depression.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2023
    Trial
  3. Article
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  5. Review
  6. Article
  7. "I'm Ready This Time": Investigating physiological and emotional habituation to repetitive social stress.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
    Article
  8. Article
  9. Article
  10. Moving toward affective immunology: Legacy and future directions.Comprehensive psychoneuroendocrinology · 2024
    Article
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  12. Review
  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Annelise A MadisonInstitute for Behavioral Medicine Research, The Ohio State University College of Medicine.
Rebecca AndridgeInstitute for Behavioral Medicine Research, The Ohio State University College of Medicine.
M Rosie ShroutInstitute for Behavioral Medicine Research, The Ohio State University College of Medicine.ORCID 0000-0001-5751-1782
Megan E RennaInstitute for Behavioral Medicine Research, The Ohio State University College of Medicine.
Jeanette M BennettDepartment of Psychological Science, The University of North Carolina at Charlotte.
Lisa M JaremkaDepartment of Psychology and Brain Sciences, University of Delaware.
Christopher P FagundesDepartment of Psychology, Rice University.ORCID 0000-0003-3173-2215
Martha A BeluryInstitute for Behavioral Medicine Research, The Ohio State University College of Medicine.
William B MalarkeyInstitute for Behavioral Medicine Research, The Ohio State University College of Medicine.
Janice K Kiecolt-GlaserInstitute for Behavioral Medicine Research, The Ohio State University College of Medicine.ORCID 0000-0003-4900-9578
Institute for Behavioral Medicine · USRice University · USUniversity of Delaware · USUniversity of North Carolina at Charlotte · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
University of Iowa Clinical and Translational Science Program (TL1)UL1RR025755 · NCRR · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2008 to 2011
$26.3M
Fatigue, Depression, and Inflammation in Cancer Survivors: A Prospective StudyR01CA131029 · NCI · OHIO STATE UNIVERSITY · PI KIECOLT-GLASER, JANICE · 2008 to 2013
$4.1M
Breast Cancer Survivors: Physical Activity, Inflammation, Fatigue, and DistressR01CA126857 · NCI · OHIO STATE UNIVERSITY · PI KIECOLT-GLASER, JANICE · 2007 to 2012
$2.6M
NRSA Training CoreTL1TR002735 · NCATS · OHIO STATE UNIVERSITY · PI BUMGARDNER, GINNY L, KIRSCHNER, LAWRENCE S · 2018 to 2022
$1.3M
Biobehavioral Influences on Cancer: Perspectives from PsychoneuroimmunologyK05CA172296 · NCI · OHIO STATE UNIVERSITY · PI KIECOLT-GLASER, JANICE · 2013 to 2017
$426k
Marital Discord, Fast Food, Obesity, and InflammationR21CA158868 · NCI · OHIO STATE UNIVERSITY · PI KIECOLT-GLASER, JANICE · 2011 to 2012
$365k
NCATS NIH HHS TL1 TR002735NCI NIH HHS K05 CA172296NCI NIH HHS P30 CA016058NCI NIH HHS R01 CA126857NCI NIH HHS R01 CA131029NCI NIH HHS R21 CA158868NCRR NIH HHS UL1 RR025755
6 · The paper itself

Abstract

The

Indexed as

DepressionStress, PsychologicalAdultHumansLongitudinal StudiesSymptom Flare Updepressioninflammationinterpersonalinterpersonal relationshipslonelinesssocialsocial-signal-transduction theory of depressionstress

Identifiers

PMID34932407
PMCPMC8985224
OpenAlexW4200405797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.