Evidence map›Paper›PMID 34932344›Full record

ArticleJournal of the American Chemical Society2022

Photomodulation of Transmembrane Transport and Potential by Stiff-Stilbene Based Bis(thio)ureas.

Sander J Wezenberg, Li-Jun Chen, Jasper E Bos, Ben L Feringa, Ethan N W Howe, Xin Wu, Maxime A Siegler, Philip A Gale

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
6.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 112 citations in OpenAlex.

  1. Light-Enhanced Chloride Transport by Thiourea-Appended Molecular Motor.Angewandte Chemie (International ed. in English) · 2026
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  8. Near-Infrared Triggered Anion Transport Induces Cancer Cell Death.Angewandte Chemie (International ed. in English) · 2026
    Article
  9. Review
  10. Hemi-Indigiosin: A pH and Red-Light Responsive Transmembrane HCl Transporter.Angewandte Chemie (International ed. in English) · 2025
    Article
  11. Review
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  13. Article
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  15. Chemically Fueled Active Transport.Angewandte Chemie (International ed. in English) · 2025
    Article
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  20. Switchable molecular tweezers: design and applications.Beilstein journal of organic chemistry · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Sander J WezenbergLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.ORCID 0000-0001-9192-3393
Li-Jun ChenSchool of Chemistry, The University of Sydney, Sydney NSW 2006, Australia.
Jasper E BosLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
Ben L FeringaStratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.ORCID 0000-0003-0588-8435
Ethan N W HoweSchool of Chemistry, The University of Sydney, Sydney NSW 2006, Australia.
Xin WuSchool of Chemistry, The University of Sydney, Sydney NSW 2006, Australia.ORCID 0000-0002-7715-8784
Maxime A SieglerDepartment of Chemistry, Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, United States.ORCID 0000-0003-4165-7810
Philip A GaleSchool of Chemistry, The University of Sydney, Sydney NSW 2006, Australia.
The University of Sydney · AULeiden University · NLJohns Hopkins University · USUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Membrane transport proteins fulfill important regulatory functions in biology with a common trait being their ability to respond to stimuli in the environment. Various small-molecule receptors, capable of mediating transmembrane transport, have been successfully developed. However, to confer stimuli-responsiveness on them poses a fundamental challenge. Here we demonstrate photocontrol of transmembrane transport and electric potential using bis(thio)ureas derived from stiff-stilbene. UV-vis and

Indexed as

Photochemical ProcessesStilbenesBiological TransportCrystallography, X-RayDensity Functional TheoryMolecular StructureThioureaStilbenesThiourea

Identifiers

PMID34932344
PMCPMC8759083
OpenAlexW4200276796

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.