Evidence map›Paper›PMID 34932317›Full record

ArticleAnalytical chemistry2022

Disassembly of Single Virus Capsids Monitored in Real Time with Multicycle Resistive-Pulse Sensing.

Jinsheng Zhou, Adam Zlotnick, Stephen C Jacobson

Abstract read
In one paragraph

Article in Analytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Integrated In-Plane Nanofluidic Devices for Resistive-Pulse Sensing.Annual review of analytical chemistry (Palo Alto, Calif.) · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Solid-State Nanopore/Nanochannel Sensing of Single Entities.Topics in current chemistry (Cham) · 2023
    Review
  9. Article
  10. Review
  11. The Dynamics of Viruslike Capsid Assembly and Disassembly.Journal of the American Chemical Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jinsheng ZhouDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405-7102, United States.ORCID 0000-0002-2694-7994
Adam ZlotnickDepartment of Molecular and Cellular Biochemistry, Indiana University, Bloomington, Indiana 47405-7003, United States.ORCID 0000-0001-9945-6267
Stephen C JacobsonDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405-7102, United States.ORCID 0000-0003-2415-041X

Funding

Single-Particle Analysis of Virus Capsids, Bacteria, and Extracellular VesiclesR35GM141922 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Stephen C Jacobson · 2021 to 2026
$3.5M
Single-Particle Analysis of Virus Capsid Assembly and Disassembly by Resistive-Pulse SensingR01GM129354 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI JACOBSON, STEPHEN C · 2018 to 2020
$925k
NIGMS NIH HHS R01 GM129354NIGMS NIH HHS R35 GM141922
6 · The paper itself

Abstract

Virus assembly and disassembly are critical steps in the virus lifecycle; however, virus disassembly is much less well understood than assembly. For hepatitis B virus (HBV) capsids, disassembly of the virus capsid in the presence of guanidine hydrochloride (GuHCl) exhibits strong hysteresis that requires additional chemical energy to initiate disassembly and disrupt the capsid structure. To study disassembly of HBV capsids, we mixed

Indexed as

CapsidVirionCapsid ProteinsHepatitis B virusVirus AssemblyCapsid Proteins

Identifiers

PMID34932317
PMCPMC8784147

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.