Evidence map›Paper›PMID 34931320›Full record

ArticleAlcoholism, clinical and experimental research2022

Abstinence versus moderation recovery pathways following resolution of a substance use problem: Prevalence, predictors, and relationship to psychosocial well-being in a U.S. national sample.

David Eddie, Brandon G Bergman, Lauren A Hoffman, John F Kelly

Abstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  6. Review
  7. Article
  8. Novel neurotherapeutic targets for substance use disorders: Neuroplasticity, neuroinflammation, gasotransmitters and non-canonical organ systems.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  9. Article
  10. Substance use negatively impacts change in reinforcement during the year following substance use treatment.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Article
  11. Article
  12. Article
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  14. Article
  15. Article
  16. Recovery capital profiles among a heterogeneous sample of individuals in recovery from alcohol problems.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024
    Article
  17. How recovery definitions vary by service use pathway: Findings from a national survey of adults.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024
    Article
  18. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

David EddieRecovery Research Institute, Center for Addiction Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-0619-7209
Brandon G BergmanRecovery Research Institute, Center for Addiction Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Lauren A HoffmanRecovery Research Institute, Center for Addiction Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
John F KellyRecovery Research Institute, Center for Addiction Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0001-6915-0750

Funding

Mentoring in Patient-Oriented Addiction ResearchK24AA022136 · NIAAA · MASSACHUSETTS GENERAL HOSPITAL · PI KELLY, JOHN F. · 2014 to 2023
$1.8M
Funded extension request for "Expanding recovery support for emerging adults with alcohol use disorder: Training in the science of social network sites"K23AA025707 · NIAAA · MASSACHUSETTS GENERAL HOSPITAL · PI BERGMAN, BRANDON G. · 2018 to 2023
$1.0M
Bringing real-time stress detection to scale: Development of a biosensor driven, stress detection classifier for smartwatchesK23AA027577 · NIAAA · MASSACHUSETTS GENERAL HOSPITAL · PI EDDIE, DAVID · 2020 to 2024
$919k
Opioid use disorder, cognition, and recovery: An investigation of neuropsychological change and associated recovery outcomes in buprenorphine and methadone treated patients [SUPPLEMENT]F32DA047741 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI HOFFMAN, LAUREN A · 2019 to 2022
$224k
Elucidating the role of cognitive and physiological aspects of affect in alcohol use relapseF32AA025251 · NIAAA · MASSACHUSETTS GENERAL HOSPITAL · PI EDDIE, DAVID · 2016 to 2017
$121k
NIAAA NIH HHS F32 AA025251NIAAA NIH HHS K23 AA025707NIAAA NIH HHS K23 AA027577NIAAA NIH HHS K24 AA022136NIAAA NIH HHS L30 AA026135NIDA NIH HHS F32 DA047741
6 · The paper itself

Abstract

backgroundMany people who report resolving an alcohol or other drug (AOD) problem continue some level of substance use. Little information exists, however, regarding the prevalence of this resolution pathway, or how continued substance use after resolving an AOD problem, relative to abstinence, relates to functioning, quality of life, and happiness (i.e., well-being). Greater knowledge of the prevalence and correlates of non-abstinent AOD problem resolution could inform public health messaging and clinical guidelines, while encouraging substance use goals likely to maximize well-being and reduce risks.

methodsWe analyzed data from a nationally representative sample of individuals who endorsed having resolved an AOD problem (N = 2002). Analyses examined: (1) The prevalence of various substance use statuses coded from lowest to highest risk: (a) continuous abstinence from all AOD since problem resolution; (b) current abstinence from all AOD with some use since problem resolution; (c) current use of a substance reported as a secondary substance; (d) current use of the individual's primary substance only; or, (e) current use of a secondary and primary substance; (2) relationships between substance use status and demographic, clinical, and service use history measures; and (3) the relationship between substance use status and well-being. Weighted, controlled, regression analyses examined the influence of independent variables on substance use status.

results(1) Prevalence: In this sample, 20.3% of patients endorsed continuous abstinence; 33.7% endorsed current abstinence; 21.0% endorsed current use of a secondary substance; 16.2% endorsed current use of a primary substance; and 8.8% endorsed current use of both a secondary and a primary substance. (2) Correlates: Lower-risk substance use status was associated with the initiation of regular substance use at an older age, more years since problem resolution, and fewer lifetime psychiatric diagnoses. (3) Well-Being: Controlling for pertinent confounds, lower-risk substance use status was independently associated with greater self-esteem, happiness, quality of life and functioning, and recovery capital, as well as less psychological distress.

conclusionsAbout half of Americans who self-identify as having resolved an AOD problem continue to use AOD in some form. It appears that, although for many abstinence is not necessary to overcome an AOD problem, it is likely to lead to better functioning and greater well-being. Further, people appear to gravitate toward abstinence/lower risk substance use with greater time since problem resolution.

Indexed as

Quality of LifeCross-Sectional StudiesFemaleFollow-Up StudiesHumansMaleSelf ConceptSubstance-Related DisordersSurveys and QuestionnairesUnited Statesabstinence versus continued substance usealcohol and other drug problem resolutionprimary and secondary substancesrecovery capitalwell-being

Identifiers

PMID34931320
PMCPMC8858850

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.