ArticleAnnals of surgical oncology2022
Surgical Outcomes and Comparative Analysis of Transduodenal Ampullectomy and Pancreaticoduodenectomy: A Single-Center Study.
Article in Annals of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Therapeutic strategies and outcomes in the management of ampullary tumours: meta-analysis.BJS open · 2026Pooled it
- Sporadic ampullary adenoma mimicking adenocarcinoma in the absence of genetic predisposition: a case report.Journal of surgical case reports · 2026Article
- Surgical outcomes of transduodenal ampullectomy for early-stage ampullary carcinoma: a comparative analysis with pancreaticoduodenectomy.International journal of surgery case reports · 2026Article
- Recurrent ascending cholangitis secondary to food reflux following transduodenal resection of an ampullary adenoma.Annals of the Royal College of Surgeons of England · 2026Article
- Pushing the Boundaries of Ampullectomy for Benign Ampullary Tumors: 25-Year Outcomes of Surgical Ampullary Resection Associated with Duodenectomy or Biliary Resection.Journal of clinical medicine · 2024Article
- Transduodenal ampullectomy is an effective surgical exploration procedure for unexplained dilation of the cholangiopancreatic duct.European journal of medical research · 2024Article
- Prognostic efficacy of lymph node parameters in resected ampullary adenocarcinoma based on long-term follow-up data after adjuvant treatment.World journal of surgical oncology · 2024Article
- Predicting lymph node metastasis using preoperative parameters in patients with T1 ampulla of vater cancer.BMC cancer · 2024Article
- Endoscopic vacuum therapy (eVAC) combined with continuous perianastomotic irrigation for prevention of anastomotic leak after surgical ampullectomy.Langenbeck's archives of surgery · 2024Article
- ASO Author Reflections: Hounsfield Unit on Preoperative Computed Tomography as a Predictive Factor of Postoperative Pancreatic Fistula.Annals of surgical oncology · 2023Article
- Short- and long-term outcomes of laparoscopic distal gastrectomy versus open distal gastrectomy for gastric cancer in overweight patients.Surgery today · 2022Article
- Comment on "Surgical Outcomes and Comparative Analysis of Transduodenal Ampullectomy and Pancreaticoduodenectomy: A Single-Center Study".Annals of surgical oncology · 2022Article
- Muscle Mass Matters in Patients with Renal Cell Carcinoma, but That Is Only the Beginning….Annals of surgical oncology · 2022Article
- ASO Author Reflections: Delayed Occurrence and Postoperative Risks of Mitomycin-C-Induced Neutropenia After Hyperthermic Intraperitoneal Chemotherapy.Annals of surgical oncology · 2022Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTransduodenal ampullectomy (TDA) is performed for adenoma or early cancer of the ampulla of Vater (AoV). This study aimed to analyze the short- and long-term outcomes of TDA (TDA group) when compared with conventional pancreaticoduodenectomy (PD) or pylorus-preserving pancreaticoduodenectomy (PD group).
methodsPatients who underwent TDA between January 2006 and December 2019, and PD cases performed for AoV malignancy with carcinoma in-situ (Tis) (high-grade dysplasia, HGD) and T1 and T2 stage from January 2010 to December 2019 were reviewed.
resultsForty-six patients underwent TDA; 21 had a benign tumor, and 25 cases with malignant tumors were compared with PD cases (n = 133). Operation time (p < 0.001), estimated blood loss (p < 0.001), length of hospital stays (p = 0.003), and overall complication rate (p < 0.001) were lower in the TDA group than in the PD group. Lymph node metastasis rates were 14.6% in pT1 and 28.9% in pT2 patients. The 5-year disease-free survival and 5-year overall survival rates for HGD/Tis and T1 tumor between the two groups were similar (TDA group vs PD group, 72.2% vs 77.7%, p = 0.550; 85.6% vs 79.2%, p = 0.816, respectively).
conclusionTDA accompanied with lymph node dissection is advisable in HGD/Tis and T1 AoV cancers in view of superior perioperative outcomes and similar long-term survival rates compared with PD.
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