Evidence map›Paper›PMID 34931130›Full record

ArticleBehavioural neurology2021

Serum Glycoproteomics and Identification of Potential Mechanisms Underlying Alzheimer's Disease.

Naphatthakarn Kerdsaeng, Sittiruk Roytrakul, Suwannee Chanprasertyothin, Piangporn Charernwat, Sirintorn Chansirikarnjana, Piyamitr Sritara, Jintana Sirivarasai

Open access · goldAbstract read
In one paragraph

Article in Behavioural neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Naphatthakarn KerdsaengDoctor of Philosophy Programme in Molecular Medicine, Faculty of Science & Faculty of Medicine Ramathibodi Hospital, Faculty of Medicine Siriraj Hospital & Faculty of Dentistry & Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-4441-8607
Sittiruk RoytrakulFunctional Ingredients and Food Innovation Research Group, National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Pathum Thani, Thailand.ORCID https://orcid.org/0000-0003-3696-8390
Suwannee ChanprasertyothinResearch & Innovation, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0003-1254-7698
Piangporn CharernwatDepartment of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-7265-1983
Sirintorn ChansirikarnjanaDepartment of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0003-3229-3963
Piyamitr SritaraDepartment of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0003-0509-8943
Jintana SirivarasaiGraduate Program in Nutrition, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-5881-6884
Mahidol University · THNational Science and Technology Development Agency · THSiriraj Hospital · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study compares glycoproteomes in Thai Alzheimer's disease (AD) patients with those of cognitively normal individuals.

methodsStudy participants included outpatients with clinically diagnosed AD (

resultsStatistical differences in age, educational level, and

conclusionFunctions and pathways associated with protein-protein interactions were identified in AD. Significant changes in these proteins can indicate the molecular mechanisms involved in the pathogenesis of AD, and they have the potential to serve as AD biomarkers. Such findings could allow us to better understand AD pathology.

Indexed as

Alzheimer DiseaseCognitive DysfunctionGlycomicsHumansProteomics

Identifiers

PMID34931130
PMCPMC8684523
OpenAlexW4200028734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.