ReviewNature reviews. Neuroscience2022
Neurons as will and representation.
Review in Nature reviews. Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- The inherent capacity of neurons to learn order relations and support abstract reasoning.Nature communications · 2026Article
- Global coincident bursts of high frequency oscillations across the human cortex coordinate large-scale memory processing.Nature communications · 2026Article
- Evolutionary Trajectories of Consciousness: From Biological Foundations to Technological Horizons.Brain sciences · 2025Review
- Human brain local field potential recordings during a battery of multilingual cognitive and eye-tracking tasks.Scientific data · 2025Article
- Scalp block improves electrophysiological stability and patient cooperation during deep brain stimulation surgery.Scientific reports · 2025Article
- Role for Left Dorsomedial Prefrontal Cortex in Self-Generated, but not Externally Cued, Language Production.Neurobiology of language (Cambridge, Mass.) · 2025Article
- The performance of mind: from movement, mental states, and consciousness.Frontiers in psychology · 2025Article
- Consciousness: a neurosurgical perspective.Acta neurochirurgica · 2023Review
- Neurons in human pre-supplementary motor area encode key computations for value-based choice.Nature human behaviour · 2023Article
- Article
- Entropy and Cross-Level Orderliness in Light of the Interconnection between the Neural System and Consciousness.Entropy (Basel, Switzerland) · 2023Review
- How far neuroscience is from understanding brains.Frontiers in systems neuroscience · 2023Article
- Bimanual motor impairments in older adults: an updated systematic review and meta-analysis.EXCLI journal · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 2 countries.
Funding
Abstract
Memory recollections and voluntary actions are often perceived as spontaneously generated irrespective of external stimuli. Although products of our neurons, they are only rarely accessible in humans at the neuronal level. Here I review insights gleaned from unique neurosurgical opportunities to record and stimulate single-neuron activity in people who can declare their thoughts, memories and wishes. I discuss evidence that the subjective experience of human recollection and that of voluntary action arise from the activity of two internal neuronal generators, the former from medial temporal lobe reactivation and the latter from frontoparietal preactivation. I characterize properties of these generators and their interaction, enabling flexible recruitment of memory-based choices for action as well as recruitment of action-based plans for the representation of conceptual knowledge in memories. Both internal generators operate on surprisingly explicit but different neuronal codes, which appear to arise with distinct single-neuron activity, often observed before participants' reports of conscious awareness. I discuss prediction of behaviour based on these codes, and the potential for their modulation. The prospects of editing human memories and volitions by enhancement, inception or deletion of specific, selected content raise therapeutic possibilities and ethical concerns.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.