Evidence map›Paper›PMID 34930931›Full record

ArticleScientific reports2021

Validation and application of a novel in vivo cervical spine kinematics analysis technique.

Zongmiao Wan, Wenjin Wang, Chao Li, Junjie Li, Jinpeng Lin, Fei Tian, Ting Zhu, Danni Wu, Luqi Guo, Shaobai Wang

Abstract readValidation Study
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Approach to assess the effect of sagittal cervical alignment on three-dimensional movement of the cervical spine in spondylosis patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Article
  3. From static X-rays to dynamic 3D tracking: A scoping review of cervical spine Imaging-Based motion assessment.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zongmiao Wan *Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Nanchang, 330000, Jiangxi, China.
Wenjin Wang *Key Laboratory of Exercise and Health Sciences of Ministry of Education, School of Kinesiology, Shanghai University of Sport, Shanghai, 20043, China.
Chao LiDepartment of Orthopedics, The First Affiliated Hospital of Nanchang University, Nanchang, 330000, Jiangxi, China.
Junjie LiKey Laboratory of Exercise and Health Sciences of Ministry of Education, School of Kinesiology, Shanghai University of Sport, Shanghai, 20043, China.
Jinpeng LinKey Laboratory of Exercise and Health Sciences of Ministry of Education, School of Kinesiology, Shanghai University of Sport, Shanghai, 20043, China.
Fei TianKey Laboratory of Exercise and Health Sciences of Ministry of Education, School of Kinesiology, Shanghai University of Sport, Shanghai, 20043, China.
Ting ZhuKey Laboratory of Exercise and Health Sciences of Ministry of Education, School of Kinesiology, Shanghai University of Sport, Shanghai, 20043, China.
Danni WuKey Laboratory of Exercise and Health Sciences of Ministry of Education, School of Kinesiology, Shanghai University of Sport, Shanghai, 20043, China.
Luqi GuoKey Laboratory of Exercise and Health Sciences of Ministry of Education, School of Kinesiology, Shanghai University of Sport, Shanghai, 20043, China.
Shaobai WangKey Laboratory of Exercise and Health Sciences of Ministry of Education, School of Kinesiology, Shanghai University of Sport, Shanghai, 20043, China. wangs@innomotion.biz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To validate the accuracy of Cone beam computed tomography (CBCT) cervical spine modeling with three dimensional (3D)-3D registration for in vivo measurements of cervical spine kinematics. CBCT model accuracy was validated by superimposition with computed tomography (CT) models in 10 healthy young adults, and then cervical vertebrae were registered in six end positions of functional movements, versus a neutral position, in 5 healthy young adults. Registration errors and six degrees of freedom (6-DOF) kinematics were calculated and reported. Relative to CT models, mean deviations of the CBCT models were < 0.6 mm. Mean registration errors between end positions and the reference neutral position were < 0.7 mm. During flexion-extension (F-E), the translation in the three directions was small, mostly < 1 mm, with coupled LB and AR both < 1°. During lateral bending (LB), the bending was distributed roughly evenly, with coupled axial rotation (AR) opposite to the LB at C1-C2, and minimal coupled F-E. During AR, most of the rotation occurred in the C1-C2 segment (29.93 ± 7.19° in left twist and 31.38 ± 8.49° in right twist) and coupled LB was observed in the direction opposite to that of the AR. Model matching demonstrated submillimeter accuracy in cervical spine kinematics data. The presently evaluated low-radiation-dose CBCT technique can be used to measure 3D spine kinematics in vivo across functional F-E, AR, and LB positions, which has been especially challenging for the upper cervical spine.

Indexed as

Biomechanical PhenomenaMovementRotationAdultCervical VertebraeFemaleHumansImaging, Three-DimensionalMaleNeckRange of Motion, ArticularReproducibility of ResultsTomography, X-Ray ComputedYoung Adult

Identifiers

PMID34930931
PMCPMC8688511

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.