ArticleScientific reports2021
Three topological features of regulatory networks control life-essential and specialized subsystems.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- FERRET: Framework to Evaluate Robustness in Regulatory Networks Using Heterogeneous Cell Types.bioRxiv : the preprint server for biology · 2026Article
- Review
- 'Intelligent' proteins.Cellular and molecular life sciences : CMLS · 2025Review
- Assessing the impact of sampling bias on node centralities in synthetic and biological networks.NPJ systems biology and applications · 2025Article
- Operating principles of interconnected feedback loops driving cell fate transitions.NPJ systems biology and applications · 2025Article
- Multi-omics analysis uncovers the transcriptional regulatory mechanism of magnesium Ions in the synthesis of active ingredients in Sophora tonkinensis.Scientific reports · 2024Article
- Topological benchmarking of algorithms to infer gene regulatory networks from single-cell RNA-seq data.Bioinformatics (Oxford, England) · 2024Article
- Review and assessment of Boolean approaches for inference of gene regulatory networks.Heliyon · 2022Review
- An updated gene regulatory network reconstruction of multidrug-resistant Pseudomonas aeruginosa CCBH4851.Memorias do Instituto Oswaldo Cruz · 2022Article
- Boolean modelling as a logic-based dynamic approach in systems medicine.Computational and structural biotechnology journal · 2022Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gene regulatory networks (GRNs) play key roles in development, phenotype plasticity, and evolution. Although graph theory has been used to explore GRNs, associations amongst topological features, transcription factors (TFs), and systems essentiality are poorly understood. Here we sought the relationship amongst the main GRN topological features that influence the control of essential and specific subsystems. We found that the K
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.