Evidence map›Paper›PMID 34930738›Full record

Observational studyBMJ open2021

Assessment of the effect of a comprehensive chest radiograph deep learning model on radiologist reports and patient outcomes: a real-world observational study.

Catherine M Jones, Luke Danaher, Michael R Milne, Cyril Tang, Jarrel Seah, Luke Oakden-Rayner, Andrew Johnson, Quinlan D Buchlak, Nazanin Esmaili

Registry-linked trialOpen access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05489471 (A Prospective Study to Assess the Impact of an Artificial Intelligence System on Reporting of Chest X-rays, Evaluate the Ability of AI Driven Worklists to Improve Reporting Times and Improve Same Day CT Pathway for Suspected Lung Cancer), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05489471 unknown statusnot on this mapstarted 2023, after this paper: background citation

A Prospective Study to Assess the Impact of an Artificial Intelligence System on Reporting of Chest X-rays, Evaluate the Ability of AI Driven Worklists to Improve Reporting Times and Improve Same Day CT Pathway for Suspected Lung Cancer

TypeobservationalSponsorHull University Teaching Hospitals NHS TrustRan2023 to 2023Enrolled20,000ConditionsArtificial IntelligenceArmsArtificial intelligence review
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Catherine M JonesAnnalise-AI, Sydney, New South Wales, Australia.
Luke DanaherI-Med Radiology Network, Sydney, New South Wales, Australia.
Michael R MilneAnnalise-AI, Sydney, New South Wales, Australia michael.milne@annalise.ai.ORCID 0000-0003-2082-5723
Cyril TangAnnalise-AI, Sydney, New South Wales, Australia.
Jarrel SeahAnnalise-AI, Sydney, New South Wales, Australia.ORCID 0000-0002-2305-7873
Luke Oakden-RaynerAustralian Institute for Machine Learning, The University of Adelaide, Adelaide, South Australia, Australia.
Andrew JohnsonAnnalise-AI, Sydney, New South Wales, Australia.
Quinlan D BuchlakAnnalise-AI, Sydney, New South Wales, Australia.
Nazanin EsmailiSchool of Medicine, The University of Notre Dame Australia School of Medicine Sydney Campus, Darlinghurst, New South Wales, Australia.
Sydney Children’s Hospitals Network · AUAlfred Health · AUAustralian Centre for Robotic Vision · AUThe University of Notre Dame Australia · AUUniversity of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesArtificial intelligence (AI) algorithms have been developed to detect imaging features on chest X-ray (CXR) with a comprehensive AI model capable of detecting 124 CXR findings being recently developed. The aim of this study was to evaluate the real-world usefulness of the model as a diagnostic assistance device for radiologists.

designThis prospective real-world multicentre study involved a group of radiologists using the model in their daily reporting workflow to report consecutive CXRs and recording their feedback on level of agreement with the model findings and whether this significantly affected their reporting.

settingThe study took place at radiology clinics and hospitals within a large radiology network in Australia between November and December 2020.

participantsEleven consultant diagnostic radiologists of varying levels of experience participated in this study. PRIMARY AND SECONDARY OUTCOME MEASURES: Proportion of CXR cases where use of the AI model led to significant material changes to the radiologist report, to patient management, or to imaging recommendations. Additionally, level of agreement between radiologists and the model findings, and radiologist attitudes towards the model were assessed.

resultsOf 2972 cases reviewed with the model, 92 cases (3.1%) had significant report changes, 43 cases (1.4%) had changed patient management and 29 cases (1.0%) had further imaging recommendations. In terms of agreement with the model, 2569 cases showed complete agreement (86.5%). 390 (13%) cases had one or more findings rejected by the radiologist. There were 16 findings across 13 cases (0.5%) deemed to be missed by the model. Nine out of 10 radiologists felt their accuracy was improved with the model and were more positive towards AI poststudy.

conclusionsUse of an AI model in a real-world reporting environment significantly improved radiologist reporting and showed good agreement with radiologists, highlighting the potential for AI diagnostic support to improve clinical practice.

Indexed as

Artificial IntelligenceDeep LearningAlgorithmsHumansProspective StudiesRadiologistsdeep learningmachine learning chest X-ray

Identifiers

PMID34930738
PMCPMC8689166
OpenAlexW4200486940

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.