ArticleReproductive health2021
Prevalence and associated factors of infertility among 20-49 year old women in Henan Province, China.
Article in Reproductive health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06996340 (Effects of White Noise on Pain, Anxiety and Comfort During in Invitro Fertilization), which is not on this map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of White Noise on Pain, Anxiety and Comfort During in Invitro Fertilization: a Randomized Controlled Trial
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 114 citations in OpenAlex.
- The Association between Circulating Lipids and Female Infertility Risk: A Univariable and Multivariable Mendelian Randomization Analysis.Nutrients · 2023Pooled it
- Pooled it
- Application of Machine Learning Algorithms for Evaluating Predictors and Developing Diagnostic Models for Female Infertility Classification.Bioengineering (Basel, Switzerland) · 2026Article
- Developing and evaluating the effectiveness of a web-based application to improve the mental health of infertile women: a multi-phase study protocol.Reproductive health · 2026Article
- Oocyte aging in focus: Environmental and endogenous stressors driving reproductive potential decline.GeroScience · 2026Review
- Distribution and trends of the global burden of female infertility attributable to sexually transmitted infections from 1990 to 2021.BMC infectious diseases · 2026Article
- Predictors of fertility preservation awareness and willingness among college students and the general population in Henan, China: a cross-sectional study.Frontiers in public health · 2026Article
- The relationship between physical activity and subjective wellbeing in infertile women: the mediating role of positive feedback and self-efficacy.Frontiers in public health · 2026Article
- Determining the relationship between sleep quality and reproductive health issues in fertile and infertile men and women: A cross-sectional study.Sleep medicine: X · 2025Article
- Education, socioeconomic status, leisure sedentary behaviors and female infertility: mendelian randomization study.BMC women's health · 2025Article
- Infections of chlamydia trachomatis, mycoplasma genitalium and neisseria gonorrhoeae among the outpatients of reproductive medicine center in Chongqing, China: a retrospective study.BMC infectious diseases · 2025Article
- A comparative study on infant growth between assisted reproductive technology pregnancy and natural pregnancy.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Global burden and trends in ovarian cancer attributable to environmental risks and occupational risks in females aged 20-49 from 1990 to 2021, with projections to 2050: a cross-sectional study.BMC public health · 2025Article
- A mixed-methods study on negative psychological states of infertile women undergoing assisted reproductive treatment.Scientific reports · 2025Article
- Nationwide prevalence of infertility in Iranian couples: findings from a 2019 study.BMC public health · 2025Article
- Association between relative fat mass and female infertility among reproductive-aged women from NHANES 2013-2020.Scientific reports · 2025Article
- The effect of educational intervention based on protection motivation theory in improving reproductive health protective behaviors: a quasi-experimental study.BMC women's health · 2025Article
- Predictive modeling of pregnancy outcomes utilizing multiple machine learning techniques for in vitro fertilization-embryo transfer.BMC pregnancy and childbirth · 2025Article
- Effects of vaginal microbiota onMicrobiology spectrum · 2025Article
- Epidemiological disease burden and annual, nationwide health insurance treatment cost of female infertility based on real-world health insurance claims data in Hungary.BMC health services research · 2025Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundInfertility is a reproductive health problem which affects not only individuals, families and social populations. Recently, the infertility rate in China has a trend of increase year by year, and few studies have reported the infertility rate in Henan Province, China. The aim of this study was to investigate the current prevalence and associated factors of infertility among women of childbearing age in Henan Province, China.
methodsThis cross-sectional study was conducted from March 2019 to October 2019. We sampled 765 women who were 20-49 years old in eight hospitals of four cities in Henan Province, China. This survey included a questionnaire, physical examination, vaginal ultrasound examinations, and serum anti-Mullerian hormone (AMH) assessment, all of which were conducted under uniform standards by trained personnel. According to the data collected from questionnaire, participants were divided into infertile and fertile groups and analyzed associated factors.
resultsAmong all the 765 participants in this study, the prevalence of infertility was 24.58%. The prevalence of primary infertility was 6.54%, and the prevalence of secondary infertility was 18.04%. In logistic multivariate regression analyses, infertility was associated with age (p < 0.001), history of gynecological surgery (p < 0.001), sweet food (p = 0.003) and decreased ovarian reserve (DOR) (p < 0.001). After further analyses, factors associated with primary infertility were age of marriage (p = 0.006), age of first sexual intercourse (p = 0.003), long-term air-conditioning environment (p < 0.001), decreased ovarian reserve (p = 0.005) and age (p = 0.002). And factors associated with secondary infertility were history of gynecological surgery (p < 0.001), decreased ovarian reserve (p = 0.002), waist-to-hip ratio (WHR) above 0.85 (p = 0.043), delivery times (p = 0.001) and ages (p < 0.001).
conclusionThe prevalence of infertility among women aged 20-49 was 24.58% and only 61.17% infertile women sought medical help in Henan Province, China. Age, history of gynecological surgeries and DOR may increase the risk of infertility. Local public health departments and medical professionals need to discharge their duty of reducing the high incidence of infertility and protecting women's reproductive health.
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