ArticleNutrition journal2021
Determinants of mortality among under-five children admitted with severe acute malnutrition in Addis Ababa, Ethiopia.
Article in Nutrition journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Pooled it
- Prevalence and risk factors of under-five mortality due to severe acute malnutrition in Africa: a systematic review and meta-analysis.Systematic reviews · 2025Pooled it
- Article
- Recovery Rate of Under-Five Children From Severe Acute Malnutrition and Its Predictors in Ethiopia: A Systematic Review and Meta-Analysis.Health science reports · 2026Review
- Incidence and predictors of treatment default among children aged 6-59 months with severe acute malnutrition in stabilisation centres in western Ethiopia: a prospective follow-up study.BMJ public health · 2026Article
- Predictors of mortality among children under five with severe acute malnutrition in intensive therapeutic nutrition units in Kasaï Central Province, 2024: a retrospective cohort study.The Pan African medical journal · 2026Article
- Survival status and predictors of mortality among children with severe acute malnutrition admitted to public health facilities at Hawassa City, Southern Ethiopia: a retrospective cohort study.Journal of health, population, and nutrition · 2025Article
- Indian perspective on childhood malnutrition: Prevalence, pathophysiology, risk factors, and prevention.World journal of clinical pediatrics · 2024Article
- Bioguided Optimization of the Nutrition-Health, Antioxidant, and Immunomodulatory Properties ofNutrients · 2024Article
- Article
- Knowledge and practices of traditional management of child malnutrition and associated pathologies in Benin.Journal of ethnobiology and ethnomedicine · 2024Article
- Epidemiological study of pediatric nutritional deficiencies: an analysis from the global burden of disease study 2019.Nutrition journal · 2024Article
- Investigating a severe acute malnutrition outbreak in Dubti District, Awsiresu Zone, Afar Region, Northeast Ethiopia (2022).Frontiers in public health · 2024Article
- Survival Status and Predictors of Tuberculosis Development Among Under 5 Children Admitted With Severe Acute Malnutrition in Ethiopia: A Retrospective Cohort Study.Global pediatric health · 2024Article
- Time to recovery and its predictors among children 6-59 months with acute malnutrition admitted to community inpatient therapeutic feeding centers in Katsina State, Northwest Nigeria: a retrospective review of health records (2010-2016).Journal of health, population, and nutrition · 2023Article
- Malnutrition among hospitalized children 12-59 months of age in Abyan and Lahj Governorates / Yemen.BMC nutrition · 2022Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundManagement of severe acute malnutrition (SAM) has been a program priority in Ethiopia, but it remains the leading cause of mortality in under-five children. Hence, this study aimed to identify the incidence density rate of mortality and determinants among under-five children with severe acute malnutrition in St. Paul's Hospital Millennium Medical College, 2012 to 2019.
methodsA retrospective cohort study was conducted and data were collected using a structured checklist from 673 charts, of which 610 charts were included in the final analysis. The Kaplan-Meier survival curve with Log-rank test was used to estimate the survival time. Bi-variable and multi-variable Cox proportional hazard regression models were fitted to identify determinants of death. Schoenfeld residuals test was used to check a proportional hazard assumption. Goodness of fit of the final model was checked using Nelson Aalen cumulative hazard function against Cox-Snell residual.
resultsIn this study, 61 (10%) children died making the incidence density rate of death 5.6 (95% CI: 4.4, 7.2) per 1000 child-days. Shock (Adjusted Hazard Ratio) [AHR] =3.2; 95% CI: 1.6, 6.3)), IV fluid infusion (AHR = 5.2; 95% CI: 2.4, 10.4), supplementing F100 (AHR = 0.12; 95%CI: 0.06, 0.23) and zinc (AHR = 0.45; 95% CI: 0.22, 0.93) were determinants of death.
conclusionThe overall proportion of deaths was within the range put forth by the Sphere standard and the national SAM management protocol. Shock and IV fluid infusion increased the hazard of death, whereas F100 & zinc were found to decrease the likelihood death. Children with SAM presented with shock should be handled carefully and IV fluids should be given with precautions.
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