Evidence map›Paper›PMID 34930291›Full record

ReviewClinical and molecular allergy : CMA2021

Quality of life in patients with allergic and immunologic skin diseases: in the eye of the beholder.

Ester Di Agosta, Lorenzo Salvati, Monica Corazza, Ilaria Baiardini, Francesca Ambrogio, Luisa Angileri, Elettra Antonelli, Federica Belluzzo, Domenico Bonamonte, Laura Bonzano and 33 more

Open access · goldAbstract readReview
In one paragraph

Review in Clinical and molecular allergy : CMA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

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  14. Urticaria.Nature reviews. Disease primers · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

43 authors at 20 institutions in 1 country.

Ester Di AgostaDepartment of Experimental and Clinical Medicine, University of Florence, Firenze, Italy.
Lorenzo SalvatiDepartment of Experimental and Clinical Medicine, University of Florence, Firenze, Italy.
Monica CorazzaSection of Dermatology and Infectious Diseases, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Ilaria BaiardiniRespiratory Unit for Continuity of Care, IRCCS Ospedale Policlinico San Martino, Department of Internal Medicine (DiMI), University of Genoa, Genova, Italy.
Francesca AmbrogioDepartment of Biomedical Science and Human Oncology, Section of Dermatology, University of Bari, Bari, Italy.
Luisa AngileriDermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.
Elettra AntonelliSection of Dermatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Federica BelluzzoASP Trapani, Trapani, Italy.
Domenico BonamonteDepartment of Biomedical Sciences and Human Oncology, Section of Dermatology, University of Bari, Bari, Italy.
Laura BonzanoDermatology Unit, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Raffaele BrancaccioDivision of Allergy and Clinical Immunology, "Santa Maria Della Speranza" Hospital, Salerno, Italy.
Paolo CusturoneSection of Dermatology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Aurora De MarcoDepartment of Biomedical Sciences and Human Oncology, Section of Dermatology, University of Bari, Bari, Italy.
Aikaterini DetorakiDepartment of Internal Medicine, Clinical Immunology, Clinical Pathology and Infectious Disease, Azienda Ospedaliera Universitaria Federico II, Napoli, Italy.
Adriana Di GuidaSection of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Napoli, Italy.
Elisabetta Di LeoSection of Allergy and Clinical Immunology, Unit of Internal Medicine-"F. Miulli" Hospital, Acquaviva Delle Fonti, Bari, Italy.
Marta FantòUnit of Allergology, Department of Dermatology, Policlinico Umberto I, Hospital-University Sapienza of Rome, Roma, Italy.
Filippo FassioAllergy and Clinical Immunology Unit, San Giovanni di Dio Hospital, Firenze, Italy.
Silvia Mariel FerrucciDermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.
Caterina FotiDepartment of Biomedical Science and Human Oncology, Section of Dermatology, University of Bari, Bari, Italy.
Rosella GalloSection of Dermatology - Department of Health Sciences, University of Genoa, Ospedale Policlinico San Martino - IRCCS, Genova, Italy.
Alessia GattaDepartment of Medicine and Science of Ageing, G. d'Annunzio University, Chieti, Italy.
Fabrizio GuarneriSection of Dermatology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Lucia GuidolinAllergy Unit, Department of Medicine, University of Verona, Verona, Italy.
Katharina HanselSection of Dermatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Donatella LamacchiaPersonalized Medicine, Asthma and Allergy, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy.
Carla LombardoAllergy Unit, Villa Igea Hospital. A.P.S.S. Trento, Trento, Italy.
Paola Lucia MinciulloDepartment of Clinical and Experimental Medicine, School and Division of Allergy and Clinical Immunology, University Hospital 'G. Martino', Messina, Italy.
Maddalena NapolitanoDepartment of Medicine and Health Science "V. Tiberio", University of Molise, Campobasso, Italy.
Alessandro PannofinoAllergology and Immunology Clinic, Operative Unit of Medicine, Policoro Hospital, Policoro, Matera, Italy.
Andrea ParavisiSection of Dermatology, Department of Health Sciences, University of Genoa, Ospedale Policlinico San Martino - IRCCS, Genova, Italy.
Roberta ParenteDepartment of Medicine, Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy.
Maria PassanteDepartment of Health Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Cataldo PatrunoDepartment of Health Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Diego PeroniSection of Pediatrics, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Cristina QuecchiaIo e l'Asma Center, Children's Hospital, ASST Spedali Civili, Brescia, Italy.
Natale SchettiniSection of Dermatology and Infectious Diseases, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Giuseppe SpadaroDepartment of Translational Medical Sciences and Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, Napoli, Italy.
Luca StingeniSection of Dermatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Daniele TarriniAllergy and Clinical Immunology Unit, Department of Clinical Medicine, Mauriziano Umberto I Hospital, University of Turin, Torino, Italy.
Marta TramontanaSection of Dermatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Eustachio NettisDepartment of Emergency and Organ Transplantation, School and Chair of Allergology and Clinical Immunology, University of Bari - Aldo Moro, Bari, Italy.
Oliviero RossiImmunoallergology Unit, SOD Immunoallergologia, Azienda Ospedaliero-Universitaria Careggi, Firenze, Italy. oliviero.rossi@unifi.it.
University of Bari Aldo Moro · ITUniversity of Perugia · ITUniversity of Messina · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITMagna Graecia University · ITOspedale Policlinico San Martino · ITPoliclinico Umberto I · ITUniversity of Ferrara · ITUniversity of Florence · ITUniversity of Naples Federico II · ITAzienda Ospedaliero-Universitaria Careggi · ITConservatorio di Musica Antonio Scontrino Trapani · ITFederico II University Hospital · ITIRCCS Humanitas Research Hospital · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITNuovo Ospedale San Giovanni di Dio · ITOspedale Generale Regionale Francesco Miulli · ITSanta Maria Nuova Hospital · ITUniversity of Chieti-Pescara · ITUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergic and immunologic skin diseases negatively impact the quality of life (QoL) of affected patients with detrimental consequences. Nonetheless, in everyday clinical practice the evaluation of QoL is often overlooked. Considering the increasing prevalence of atopic dermatitis, allergic contact dermatitis, hereditary angioedema, cutaneous mastocytosis, and urticaria, it is essential to determine the effects of allergic and immunologic skin diseases on QoL. A joint meeting (GET TOGETHER 2021) of the Italian Society of Allergology, Asthma and Clinical Immunology (SIAAIC) and the Italian Society of Allergological, Occupational and Environmental Dermatology (SIDAPA) aimed to summarize the features of the main QoL tools used in these diseases and to describe the extent of QoL impairment as well as the impact of treatments on QoL, particularly biologic therapies. The assessment of QoL in patients with allergic and immunologic skin diseases relies on generic, organ-specific and disease-specific questionnaires. While generic and organ-specific questionnaires allow comparison between different diseases, disease-specific questionnaires are designed and validated for specific cohorts: the QoL Index for Atopic Dermatitis (QoLIAD) and the Childhood Atopic Dermatitis Impact Scale (CADIS) in atopic dermatitis, the ACD-11 in allergic contact dermatitis, the Angioedema QoL Questionnaire (AE-QoL) and the Hereditary Angioedema QoL questionnaire (HAE-QoL) in hereditary angioedema, the Mastocytosis QoL Questionnaires (MCQoL e MQLQ) in cutaneous mastocytosis, and the Chronic Urticaria QoL questionnaire (CU-Q2oL) in urticaria. Among the many factors that variably contribute to QoL impairment, pruritus can represent the leading cause of patient discomfort. Biologic therapies significantly ameliorate QoL in atopic dermatitis, hereditary angioedema, mastocytosis and chronic urticaria. In general, adequate management strategies are essential for improving QoL in patients with allergic and immunologic skin diseases.

Indexed as

Allergic contact dermatitisAllergyAtopic dermatitisCutaneous mastocytosisHereditary angioedemaQuality of lifeSkinUrticaria

Identifiers

PMID34930291
PMCPMC8690422
OpenAlexW4200317402

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.